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Acta Cryst. (2008). E64, o810-o811  [ doi:10.1107/S1600536808009306 ]

N-(3-Oxo-1-thia-4-azaspiro[4.5]dec-4-yl)-6-phenylimidazo[2,1-b][1,3]thiazole-3-acetamide hemihydrate

M. Akkurt, S. P. Yalçin, N. U. Güzeldemirci and O. Büyükgüngör

Abstract: The title compound, C21H22N4O2S2·0.5H2O, crystallizes with two molecules in the asymmetric unit. The dihedral angles between the phenyl and imidazothiazole ring systems are 19.16 (9) and 21.37 (9)°. In the imidazothiazole ring systems, the cyclohexane rings adopt chair conformations, while the thiazole rings have distorted envelope conformations. The two molecules are stabilized by intramolecular N-H...O, O-H...O and C-H...S interactions and the crystal structure is stabilized by intermolecular N-H...O, O-H...O, C-H...O and C-H...N interactions.


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