Acta Cryst. (2008). E64, o1887  [ doi:10.1107/S1600536808027803 ]

(2R)-2-Cinnamoylamino-N-[5-(4-methoxyphenyl)-1,3,4-thiadiazol-2-yl]propanamide

S.-H. Li, G. Li, H.-M. Huang, G.-G. Tu and C.-M. Liu

Abstract: The asymmetric unit of the title compound, C₂₁H₂₀N₄O₃S, contains two independent molecules. The dihedral angles between the two benzene rings are 47.6 (1) and 30.2 (1)°, the corresponding values between the p-methoxybenzene and thiadiazol rings are 12.3 (1) and 24.7 (1)°, respectively, for the two molecules. The conformations of the N-H and C=O bonds are anti with respect to each other. The enone groups show a trans configuration. The crystal structure is stabilized by N-HO and N-HN interactions. The absolute structure could not be determined from the X-ray data but the absolute configuration has been assigned by reference to an unchanging chiral centre in the synthetic procedure.

Online 6 September 2008

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