Received 1 September 2008
In the structure of the title compound, C20H15BrN4O·C2H6O, the hydrogenated pyridinone ring adopts an envelope conformation. The dihedral angle between the bromo-substituted phenyl ring and the pyrazole ring is 79.6 (1)°, and that between the non-substituted phenyl ring and the pyrazole ring is 51.2 (1)°. In the crystal structure, molecules are linked via intermolecular N-HO and O-HN hydrogen bonds. A short intermolecular NBr contact [3.213 (4) Å] is present in the crystal structure.
Data collection: SMART (Bruker, 1997); cell refinement: SAINT (Bruker, 1997); data reduction: SAINT; program(s) used to solve structure: SHELXS97 (Sheldrick, 2008); program(s) used to refine structure: SHELXL97 (Sheldrick, 2008); molecular graphics: ORTEP-3 for Windows (Farrugia, 1997); software used to prepare material for publication: WinGX (Farrugia, 1999).
Supplementary data and figures for this paper are available from the IUCr electronic archives (Reference: XU2452 ).
This work was supported by the National Natural Science Foundation of China (No. 20772025) and the Program for Science and Technology Innovation Talents in Universities of Henan Province (No. 2008HASTIT006).
Bruker (1997). SADABS, SMART and SAINT. Bruker AXS Inc., Madison, Wisconsin, USA.
Falcó, J. L., Lloveras, M., Buira, I., Teixidó, J., Borrell, J. I., Méndez, E., Terencio, J., Palomer, A. & Guglietta, A. (2005). Eur. J. Med. Chem. 40, 1179-1187.
Farrugia, L. J. (1997). J. Appl. Cryst. 30, 565.
Farrugia, L. J. (1999). J. Appl. Cryst. 32, 837-838.
Kung, D. W. & Wager, T. T. (2007). US Patent 7 300 944.
Sheldrick, G. M. (2008). Acta Cryst. A64, 112-122.