[HTML version][PDF version][CIF][3d view][Structure Factors][Supplementary Material][CIF check Report][Issue contents]  [Open access]

[Contents scheme]

Acta Cryst. (2008). E64, o2120  [ doi:10.1107/S1600536808033205 ]

(Anthracen-9-yl)(piperidin-1-yl)methanone

H.-Y. Hu, Y.-C. Huang, H.-T. Yu and Y. Zhang

Abstract: The title compound, C20H19NO, is a substructure of CP-640186, a potent inhibitor of mammalian acetyl-coenzyme A carboxylases. In the crystal structure, the amide group forms a dihedral angle of 87.0 (1)° with the plane of the anthracene unit and the piperidine ring adopts a chair conformation. Molecules are arranged into layers parallel to (100) and adjacent anthracene units within layers form dihedral angles of 13.2 (1)°. C-H...O interactions from the piperidine rings to the C=O group of the amide are observed between layers.

Online 15 October 2008


Copyright © International Union of Crystallography
IUCr Webmaster