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Acta Cryst. (2008). E64, o2050  [ doi:10.1107/S1600536808030018 ]

(Z)-Methyl 4-[3-(3-oxoquinuclidin-2-ylidenemethyl)-1H-indol-1-ylmethyl]benzoate

T. R. Y. Reddy, N. R. Penthala, S. Parkin and P. A. Crooks

Abstract: The title compound, C25H24N2O3 was prepared by the reaction of (Z)-2-(1H-indol-3-ylmethylene)-1-azabicyclo[2.2.2]octan-3-one with methyl p-(bromomethyl)benzoate, under phase-transfer catalytic (PTC) conditions using triethylbenzylammonium chloride and 50% w/v aqueous NaOH solution in dichloromethane. The crystal structure indicates the presence of a double bond with Z geometry connecting the azabicyclic and indole groups.

Online 4 October 2008


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