Acta Cryst. (2008). E64, o2261  [ doi:10.1107/S1600536808035411 ]

2-Methyl-2-(4-nitrophenoxy)propanoic acid

G. Navarrete-Vázquez, H. Torres-Gómez, S. Hidalgo-Figueroa and H. Tlahuext

Abstract: The title compound, C₁₀H₁₁NO₅, is of interest with respect to its antidyslipidemic activity. It was prepared by reaction of 4-nitrophenol with ethyl 2-bromo-2-methylpropionate followed by ethyl ester hydrolysis. In the crystal, molecules are linked into centrosymmetric dimers by intermolecular O-HO hydrogen bonds and the dimers are connected into chains by weak C-HO interactions. The packing is further stabilized by offset - interactions between adjacent benzene rings with a centroid-centroid distance of 3.8643 (17) Å.

Online 8 November 2008

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