Acta Cryst. (2009). E65, o984  [ doi:10.1107/S1600536809012173 ]

2-Methyl-1,10b-dihydro-5H-pyrazolo[1,5-c][1,3]benzoxazin-5-one

V. Kettmann and J. Svetlík

Abstract: In the title compound, C₁₁H₁₀N₂O₂, a potential inhibitor of the cyclooxygenase-2 isoenzyme, the pyrazoline ring exists in a flat-envelope conformation while the puckering of the central oxazine ring is more severe. As a result, the molecule as a whole is non-planar. The formal sp³ pyrazoline N atom is sp² hybridized, with the lone-pair electrons delocalized through conjugation with the carbonyl group rather than the double bond of the pyrazoline ring.

Online 8 April 2009

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