Acta Cryst. (2009). E65, o1325-o1326  [ doi:10.1107/S1600536809017905 ]

Capecitabine from X-ray powder synchrotron data

J. Rohlicek, M. Husak, A. Gavenda, A. Jegorov, B. Kratochvil and A. Fitch

Abstract: In the title compound [systematic name 5-deoxy-5-fluoro-N-(pentyloxycarbonyl)cytidine], C₁₅H₂₂FN₃O₆, the pentyl chain is disordered over two positions with refined occupancies of 0.53 (5) and 0.47 (5). The furan ring assumes an envelope conformation. In the crystal, intermolecular N-HO hydrogen bonds link the molecules into chains propagating along the b axis. The crystal packing exhibits electrostatic interactions between the 5-fluoropyrimidin-2(1H)-one fragments of neighbouring molecules as indicated by short OC [2.875 (3) and 2.961 (3) Å] and FC [2.886 (3) Å] contacts.

Online 20 May 2009

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