Acta Cryst. (2009). E65, o1547  [ doi:10.1107/S1600536809020996 ]

1,2,5-Oxadiazolo[3,4-b]glycyrrhetinic acid

J. Hu, L. Yu, R. Wang and Y. Ju

Abstract: The title compound [systematic name: 11-oxo-2,3-(oxydinitrilo)olean-12-en-29-oic acid], C₃₀H₄₂N₂O₄, contains a linear array of five six-membered rings and a five-membered heterocyclic ring. The C ring, containing an ,-unsaturated ketone, has a slightly distorted half-chair conformation, as does the A ring, with N-C-C angles 125.3 (5), 111.2 (4), 124.9 (5) and 109.2 (5)°, while the other three six-membered rings adopt chair conformations. The enantiomer has been assigned by reference to unchanging chiral centres in the synthetic procedure. An intramolecular C-HO interaction is present. In the crystal structure, intermolecular O-HO hydrogen bonds link the molecules.

Online 10 June 2009

Copyright © International Union of Crystallography
IUCr Webmaster