Received 2 February 2010
In the title compound, C17H18N4O2S·H2O, the thiourea derivative is almost planar, with an r.m.s. deviation for the non-H atoms of 0.057 Å. The hydroxyl groups lie to the same side of the molecule as the thione S atom, a conformation that allows the formation of intramolecular O-HS and O-HN hydrogen bonds. In the crystal structure, the thiourea and water molecules self-assemble into a two-dimensional array by a combination of Owater-HOhydroxyl, N-HOwater and Owater-HS hydrogen bonds and C-H interactions.
For background and recent studies of the biological activity of organotin compounds, see: Gielen & Tiekink (2005); Affan et al. (2009). For the structure of the ketone analogue of the title compound, see: Zukerman-Schpector et al. (2009).
Data collection: APEX2 (Bruker, 2007); cell refinement: SAINT (Bruker, 2007); data reduction: SAINT; program(s) used to solve structure: SHELXS86 (Sheldrick, 2008); program(s) used to refine structure: SHELXL97 (Sheldrick, 2008); molecular graphics: ORTEP-3 (Farrugia, 1997) and DIAMOND (Brandenburg, 2006); software used to prepare material for publication: SHELXL97.
Supplementary data and figures for this paper are available from the IUCr electronic archives (Reference: HB5327 ).
The authors express their gratitude to the Ministry of Science, Technology and Innovation (MOSTI) for a research grant (No. 06-01-09-SF0046), and to Universiti Malaysia Sarawak (UNIMAS) for financial support.
Affan, M. A., Foo, S. W., Jusoh, I., Hanapi, S. & Tiekink, E. R. T. (2009). Inorg. Chim. Acta, 362, 5031-5037.
Brandenburg, K. (2006). DIAMOND. Crystal Impact GbR, Bonn, Germany.
Bruker (2007). APEX2 and SAINT. Bruker AXS Inc., Madison, Wisconsin, USA.
Farrugia, L. J. (1997). J. Appl. Cryst. 30, 565.
Gielen, M. & Tiekink, E. R. T. (2005). Editors. Metallotherapeutic Drugs and Metal-Based Diagnostic Agents: The Use of Metals in Medicine, pp. 421-439. Chichester: John Wiley & Sons.
Sheldrick, G. M. (1996). SADABS. University of Göttingen, Germany.
Sheldrick, G. M. (2008). Acta Cryst. A64, 112-122.
Zukerman-Schpector, J., Affan, M. A., Foo, S. W. & Tiekink, E. R. T. (2009). Acta Cryst. E65, o2951.