Received 21 January 2010
In the title 1:1 adduct, C6H9N3·C7H7NO2, the crystal structure is stabilized by hydrogen bonds involving two different R22(8) motifs. One of them is formed by the interaction of 2-amino-4,6-dimethylpyrimidine (AMPY) with the carboxyl group of anthranilic acid (AA) through N-HO and O-HN hydrogen bonds, whereas the other is formed through the interaction of two centrosymmetrically related pyrimidines involving N-HN hydrogen bonds. These two combined motifs form a heterotetramer. The heterotetramer sheets are stacked into three-dimensional network.
For the importance the reaction of aminopyrimidine derivatives and carboxylic acids in protein-nucleic acid recognition and drug binding, see: Hunt et al. (1980); Baker & Santi (1965). For pyrimidine-carboxylic acid interactions, see: Allen et al. (1999). For co-crystals of AMPY, see: Balasubramani et al. (2005, 2006); Devi & Muthiah (2007). For hydrogen-bonded synthons, see: Thakur & Desiraju (2008). For packing patterns in 2-amino-4,6-dimethylpyrimidine-salicylate, see: Muthiah et al. (2006). For typical geometric parameters in aromatic stacking, see: Hunter (1994).
Data collection: APEX2 (Bruker, 2008); cell refinement: SAINT (Bruker, 2008); data reduction: SAINT; program(s) used to solve structure: SHELXS97 (Sheldrick, 2008); program(s) used to refine structure: SHELXL97 (Sheldrick, 2008); molecular graphics: PLATON (Spek, 2009); software used to prepare material for publication: PLATON.
Supplementary data and figures for this paper are available from the IUCr electronic archives (Reference: KP2248 ).
The authors thank the DST-India (FIST programme) for the use of diffractometer at the School of Chemistry, Bharathidasan University.
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