Received 15 April 2010
The title compound, C16H14O5, was prepared from the reaction of 3-carbethoxycoumarin with furan in the presence of AlCl3 as catalyst. In the crystal, intermolecular C-HO hydrogen-bonding interactions between four molecules lead to a tetramer in the unit cell. The furan ring is antiperiplanar [C-C-C-O = 167.9 (13)°] and the ethoxycarbonyl group is (-)anticlinal [C-C-C-O = -128.6 (14)°] to the lactone ring.
For the medicinal and biological activity of coumarins and their derivatives, see: Borges et al. (2005); Kontogiorgis & Hadjipavlou-Litina (2005); Gursoy & Karali (2003); Prabhakar et al. (2010). For the assignment of conformations and the orientation of the substituents, see: Nardelli (1983, 1995); Klyne & Prelog (1960).
Data collection: SMART (Bruker, 2003); cell refinement: SAINT (Bruker, 2003); data reduction: SAINT; program(s) used to solve structure: SHELXS97 (Sheldrick, 2008); program(s) used to refine structure: SHELXL97 (Sheldrick, 2008); molecular graphics: SHELXTL (Sheldrick, 2008); software used to prepare material for publication: SHELXTL.
Supplementary data and figures for this paper are available from the IUCr electronic archives (Reference: DS2028 ).
We thank the Director, Institute of Life Sciences, for support and also the Dean, School of Chemistry, University of Hyderabad, for the X-ray crystallographic data.
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