Received 19 April 2010
aShanghai Institute of Materia Medica, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, 555 Zuchongzhi Road, Shanghai 201203, People's Republic of China, and bCentral Research Institute, Shanghai Pharmaceutical (Group) Co. Ltd, 555 Zuchongzhi Road, Shanghai 201203, People's Republic of China
Correspondence e-mail: firstname.lastname@example.org
The title compound, C18H23N3O3, crystallized with two independent molecules (A and B) in the asymmetric unit. The phenyl ring and the 1,2,4-oxadiazole ring are inclined to one another by 19.9 (3)° in molecule A and 7.3 (3)° in molecule B. The absolute structure of the title compound was referred to the transfered chiral center (S) of one of the starting reactants. In the crystal, A molecules are linked by C-HN interactions involving the two oxadiazole N atoms.
For the oxadiazole nucleus as a core structural unit of various muscarinic agonists, see: Orlek & Blaney (1991). For benzodiazepine receptor partial agonists, see: Watjen & Baker (1989). For dopamine transporters, see: Gray & Abrahm (1993). For 5-HT agonists, see: Swain & Baker (1991). For inhibitors of HIV, see: Matthew et al. (2007). For GABAA receptor agonists, see: Michaela & Holger (2008). For bond-length data, see: Allen et al. (1987).
Data collection: SMART (Bruker, 2007); cell refinement: SAINT (Bruker, 2007); data reduction: SAINT; program(s) used to solve structure: SHELXS97 (Sheldrick, 2008); program(s) used to refine structure: SHELXL97 (Sheldrick, 2008); molecular graphics: PLATON (Spek, 2009); software used to prepare material for publication: SHELXL97 and PLATON.
Supplementary data and figures for this paper are available from the IUCr electronic archives (Reference: SU2175 ).
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