Acta Cryst. (2010). E66, o2852  [ doi:10.1107/S1600536810041085 ]

6-Hydroxy-4-(pyridin-3-yl)-5-(2-thienylcarbonyl)-6-trifluoromethyl-3,4,5,6-tetrahydropyrimidin-2(1H)-one

G.-C. Li, Z.-Y. Ju, H.-S. Wang, Y.-J. Niu and F.-L. Yang

Abstract: In the title compound, C₁₅H₁₂F₃N₃O₃S, the pyrimidine ring adopts a half-chair conformation with the mean plane formed by the ring atoms excluding the C atom bonded to thiophene-2-carbonyl group lying nearly perpendicular to the pyridine and thiophene rings, making dihedral angles of 84.91 (4) and 87.40 (5)°, respectively. The dihedral angle between the pyridine and thiophene rings is 54.44 (5)°. The crystal structure is stabilized by intermolecular O-HO and N-HN hydrogen bonds and weak C-HO interactions further consolidate the structure.

Online 20 October 2010

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