Acta Cryst. (2010). E66, o3017-o3018 [ doi:10.1107/S1600536810043965 ]
Abstract: In the title isoniazid derivative, C13H11N3O4·2H2O, the Schiff base molecule exists in an E configuration with respect to the acyclic C=N bond. An intramolecular O-HN hydrogen bond forms a six-membered ring, producing an S(6) ring motif. The essentially planar pyridine ring [maximum deviation = 0.0119 (8) Å] is inclined at a dihedral angle of 7.30 (4)° with respect to the benzene ring. In the crystal, intermolecular O-HN, O-HO, N-HO and C-HO hydrogen bonds link the molecules into two-dimensional arrays lying parallel to the (10) plane. These arrays are further interconnected into a three-dimensional extended network via O-HO and C-HO hydrogen bonds. A weak intermolecular - interaction [centroid-to-centroid distance = 3.5627 (5) Å] is also observed.
Online 31 October 2010
Copyright © International Union of Crystallography