Diaquabis[8-ethyl-5-oxo-2-(piperazin-4-ium-1-yl)-5,8-dihydropyrido[2,3-d]pyrimidine-6-carboxylato]copper(II) bis[4-(4-carboxyphenoxy)benzoate]

In the title compound, [Cu(C14H17N5O3)2(H2O)2](C14H9O5)2, the Cu2+ atom, located on an inversion centre, exhibits a distorted octahedral geometry, coordinated by four O atoms from two pipemidic acid ligands in equatorial positions and two water molecules in axial positions. The pipemidic acid ligand acts a bidentate ligand and the single deprotonated 4,4′-oxydibenzoic acid acts as an anion. Classical N—H⋯O and O—H⋯O hydrogen bonds are present in the crystal structure.

In the title compound, [Cu(C 14 H 17 N 5 O 3 ) 2 (H 2 O) 2 ](C 14 H 9 O 5 ) 2 , the Cu 2+ atom, located on an inversion centre, exhibits a distorted octahedral geometry, coordinated by four O atoms from two pipemidic acid ligands in equatorial positions and two water molecules in axial positions. The pipemidic acid ligand acts a bidentate ligand and the single deprotonated 4,4 0oxydibenzoic acid acts as an anion. Classical N-HÁ Á ÁO and O-HÁ Á ÁO hydrogen bonds are present in the crystal structure.

Related literature
For general background to the use of quinolones in the treatment of infections, see: Mizuki et al. (1996).

Experimental
A mixture of CuI (0.095 g, 0.5 mmol), Hppa (0.089 g, 0.25 mmol), H 2 oba (0.0645 g, 0.25 mmol) and water (8 ml) was stirred for 30 min in air. The mixture was then transferred to a 18 ml teflon-lined hydrothermal bomb. The bomb was kept at 393 K for 120 h under autogenous pressure. Upon cooling, blue block of I were obtained from the reaction mixture.

Refinement
The H atoms bonded to C atoms were positioned geometrically and refined using a riding model approximation [aromatic C-H = 0.93Å, aliphatic C-H = 0.96Å-0.97Å], with U iso (H) = 1.2-1.5U eq (C). The H atoms based on N atoms were located in a difference Fourier map and were refined with a distance restraint of N-H = 0.90Å and with U iso (H) = 1.2U eq (N).
The H atoms bonded to O atoms were located in a difference Fourier maps and refined with O-H distance restraints of 0.81 (3)Å and with U iso (H) = 1.3U eq (O). The H atoms bonded to OW atoms were located in a difference Fourier maps and refined with OW-H = 0.845Å-0.855Å and U iso (H) = 1-1.2U eq (OW).
supplementary materials sup-2 Figures Fig. 1. Asymmetric unit of title compound with the atom numbering scheme. Displacement ellipsoids are drawn at 50% probability level. H atoms are presented as a small spheres of arbitrary radius. Symmetry code: (i) -x, -y, -z.