Received 14 March 2011
The molecule of the title compound, C9H6N2O2, is almost planar, with a dihedral angle of 3.0 (9)° between the pyridine and benzene rings.
For the first synthesis of 8-nitroquinoline, see: Königs (1879). The crystal studied was synthesised according to the method of Yale & Bernstein (1948). For the pharmacological activity of quinoline derivatives, see: Franck et al. (2004); Zouhiri et al. (2005). For standard bond lengths, see: Allen et al. (1987).
Data collection: SMART (Bruker, 2001); cell refinement: SAINT-Plus (Bruker, 2003); data reduction: SAINT-Plus; program(s) used to solve structure: SHELXTL (Sheldrick, 2008); program(s) used to refine structure: SHELXTL; molecular graphics: SHELXTL; software used to prepare material for publication: SHELXTL.
Supplementary data and figures for this paper are available from the IUCr electronic archives (Reference: HG5010 ).
The authors thank Liaoning University of Traditional Chinese Medicine for supporting this study (No. YXRC0920).
Allen, F. H., Kennard, O., Watson, D. G., Brammer, L., Orpen, A. G. & Taylor, R. (1987). J. Chem. Soc. Perkin. Trans. 2, pp. S1-19.
Bruker (2001). SMART. Bruker AXS Inc., Madison, Wisconsin, USA.
Bruker (2003). SAINT-Plus. Bruker AXS Inc., Madison, Wisconsin, USA.
Franck, X., Fournet, A., Prina, E., Mahieux, R., Hocquemiller, R. & Figadere, B. (2004). Bioorg. Med. Chem. Lett. 14, 3635-3638.
Königs, W. (1879). Chem. Ber. 12, 448-451.
Sheldrick, G. M. (2008). Acta Cryst. A64, 112-122.
Yale, H. L. & Bernstein, J. (1948). J. Am. Chem. Soc. 70, 254-254.
Zouhiri, F., Danet, M., Benard, C., Normand-Bayle, M., Mouscadet, J. F., Leh, H., Thomas, C. M., Mbemba, G., D'Angelo, J. & Desmaele, D. (2005). Tetrahedron Lett. 46, 2201-2205.