Acta Cryst. (2011). E67, o759  [ doi:10.1107/S1600536811006933 ]

4-(3-Fluorophenyl)-6-hydroxy-5-(thiophen-2-ylcarbonyl)-6-trifluoromethyl-1,3-diazinan-2-one

Q. He, J. Li and B.-J. Huang

Abstract: In the title compound, C₁₆H₁₂F₄N₂O₃S, the pyrimidine ring adopts a half-chair conformation; the mean plane formed by the ring atoms excluding the C atom bonded to the thiophen-2-ylcarbonyl group has an r.m.s. deviation of 0.059 Å. The dihedral angle between the benzene and thiophene rings is 62.26 (7)°. The molecular conformation is stabilized by an intramolecular O-HO hydrogen bond, generating an S(6) ring. In the crystal, adjacent molecules are connected via a centrosymmetric R₂²(6) motif, formed by N-HO hydrogen bonds.

Online 2 March 2011

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