Received 22 February 2011
aFaculty of Light Industry and Chemical Engineering, Guangdong University of Technology, Guangzhou 510006, People's Republic of China,bSchool of Pharmaceutical Sciences, Sun Yat-Sen University, Guangzhou 510275, People's Republic of China, and cInstrumental Analysis & Research Center, Sun Yat-Sen University, Guangzhou 510275, People's Republic of China
Correspondence e-mail: firstname.lastname@example.org
In the title compound, C10H6Cl3NO2, a mean plane fitted through all non-H atoms has an r.m.s. deviation of 0.035 Å. In the crystal, adjacent molecules are connected by O-HO hydrogen bonds and - stacking interactions [centroid-centroid distance = 3.650 (1) Å], resulting in an infinite chain which propagates in the b-axis direction.
The title compound was obtained as an unexpected product from an attempt to synthesize a Top1 (DNA topoisomerase IB) inhibitor For general background to Top1, see: Pommier (2006). For the synthesis, see: Shen et al. (2008); Cheng et al. (2008).
Data collection: CrysAlis PRO (Oxford Diffraction, 2006); cell refinement: CrysAlis PRO; data reduction: CrysAlis PRO; program(s) used to solve structure: SHELXTL (Sheldrick, 2008); program(s) used to refine structure: SHELXTL; molecular graphics: SHELXTL; software used to prepare material for publication: SHELXTL and publCIF (Westrip, 2010).
Supplementary data and figures for this paper are available from the IUCr electronic archives (Reference: NK2089 ).
The authors acknowledge financial support from the National Natural Science Foundation of China (No. 30801425) and Guangdong Natural Science Fund (No. 10151008901000022).
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