Acta Cryst. (2011). E67, o1290  [ doi:10.1107/S1600536811015224 ]

11,20-Dihydroxy-3-oxopregna-1,4-dien-21-oic acid monohydrate

Z. Guo, S. Tang and H. Duan

Abstract: The title compound, C₂₁H₂₈O₅·H₂O, is the hydrate of a steroid derivative and was obtained by degradation of solid prednisolone sodium phosphate. The six C atoms in ring A are nearly co-planar with a mean deviation of 0.015 Å. Rings B and C are both in chair conformations, while ring D has an envelope form. In the crystal, intermolecular O-HO hydrogen-bonding interactions occur between the hydroxy groups, carbonyl O atoms and solvent water molecules, resulting in an overall three-dimensional structure.

Online 7 May 2011

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