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Journal logoCRYSTALLOGRAPHIC
COMMUNICATIONS
ISSN: 2056-9890
Volume 67| Part 7| July 2011| Pages o1719-o1720

9-(3,4-Dimeth­­oxy­phen­yl)-3,3,6,6-tetra­methyl-4,5,6,9-tetra­hydro-3H-xanthene-1,8(2H,7H)-dione

aSchool of Industrial Technology, Universiti Sains Malaysia, 11800 USM, Penang, Malaysia, and bX-ray Crystallography Unit, School of Physics, Universiti Sains Malaysia, 11800 USM, Penang, Malaysia
*Correspondence e-mail: hkfun@usm.my

(Received 20 May 2011; accepted 14 June 2011; online 18 June 2011)

The asymmetric unit of the title xanthene compound, C25H30O5, contains two mol­ecules in which the pyran ring and the dimeth­oxy­phenyl ring are nearly perpendicular to one another [dihedral angles = 86.81 (8) and 84.45 (9)°]. One of the meth­oxy groups in one mol­ecule is twisted away from the phenyl ring [C—O—C—C torsion angle = −103.40 (16)°]. The pyran ring adopts a boat conformation whereas the two fused cyclo­hexane rings adopt envelope conformations in both mol­ecules. In the crystal, mol­ecules are linked into a three-dimensional network by C—H⋯O hydrogen bonds.

Related literature

For applications of xanthene derivatives, see: Lambert et al. (1997[Lambert, R. W., Martin, J. A., Merrett, J. H., Parkes, K. E. B. & Thomas, G. J. (1997). PCT Int. Appl. WO 9 706 178.]); Hideo (1981[Hideo, T. (1981). Jpn Tokkyo Koho JP 56 005 480.]); Poupelin et al. (1978[Poupelin, J. P., Saint-Ruft, G., Foussard-Blanpin, O., Narcisse, G., Uchida-Ernouf, G. & Lacroix, R. (1978). Eur. J. Med. Chem. 13, 67-71.]); Menchen et al. (2003[Menchen, S. M., Benson, S. C., Lam, J. Y. L., Zhen, W., Sun, D., Rosenblum, B. B., Khan, S. H. & Taing, M. (2003). US Patent 6 583 168.]); Banerjee & Mukherjee (1981[Banerjee, A. & Mukherjee, A. K. (1981). Stain Technol. 56, 83-85.]); Ravindranath & Seshadri (1973)[Ravindranath, B. & Seshadri, T. R. (1973). Phytochemistry, 12, 2781-2788.]. For the synthesis of xanthene and 1,8-dioxoocta­hydroxanthene derivatives with or without the use of a catalyst, see: Fan et al. (2005[Fan, X.-S., Li, Y.-Z., Zhang, X.-Y., Hu, X.-Y. & Wang, J.-J. (2005). Chin. Chem. Lett. 16, 897.]); Jin et al. (2005[Jin, T. S., Zang, J. S., Wang, A. Q. & Li, T. S. (2005). Synth. Commun. 35, 2339-2345.]); Srihari et al. (2008[Srihari, P., Mandal, S. S. & Reddy, J. S. S. (2008). Chin. Chem. Lett. 19, 771-774.]). For a related structure, see: Mehdi et al. (2011[Mehdi, S. H., Hashim, R., Ghalib, R. M., Yeap, C. S. & Fun, H.-K. (2011). Acta Cryst. E67, o1449.]). For the stability of the temperature controller used in the data collection, see: Cosier & Glazer (1986[Cosier, J. & Glazer, A. M. (1986). J. Appl. Cryst. 19, 105-107.]). For ring conformations, see: Cremer & Pople (1975[Cremer, D. & Pople, J. A. (1975). J. Am. Chem. Soc. 97, 1354-1358.]).

[Scheme 1]

Experimental

Crystal data
  • C25H30O5

  • Mr = 410.49

  • Triclinic, [P \overline 1]

  • a = 9.4895 (7) Å

  • b = 10.2283 (7) Å

  • c = 23.3218 (16) Å

  • α = 85.872 (4)°

  • β = 86.537 (4)°

  • γ = 74.425 (3)°

  • V = 2172.9 (3) Å3

  • Z = 4

  • Mo Kα radiation

  • μ = 0.09 mm−1

  • T = 100 K

  • 0.42 × 0.39 × 0.20 mm

Data collection
  • Bruker SMART APEXII CCD diffractometer

  • Absorption correction: multi-scan (SADABS; Bruker, 2009[Bruker (2009). APEX2, SAINT and SADABS. Bruker AXS Inc., Madison, Wisconsin, USA.]) Tmin = 0.965, Tmax = 0.983

  • 44431 measured reflections

  • 11497 independent reflections

  • 8871 reflections with I > 2σ(I)

  • Rint = 0.040

Refinement
  • R[F2 > 2σ(F2)] = 0.054

  • wR(F2) = 0.127

  • S = 1.01

  • 11497 reflections

  • 553 parameters

  • H-atom parameters constrained

  • Δρmax = 0.42 e Å−3

  • Δρmin = −0.28 e Å−3

Table 1
Hydrogen-bond geometry (Å, °)

D—H⋯A D—H H⋯A DA D—H⋯A
C10A—H10A⋯O4Ai 0.99 2.38 3.2817 (19) 152
C18A—H18A⋯O2Aii 0.95 2.35 3.2943 (19) 176
C18B—H18B⋯O2Biii 0.95 2.45 3.4000 (19) 175
C20A—H20A⋯O3Aiv 0.98 2.59 3.4144 (19) 142
C24B—H24D⋯O4Av 0.98 2.48 3.453 (2) 171
Symmetry codes: (i) x, y-1, z; (ii) -x, -y+1, -z; (iii) -x+1, -y, -z+1; (iv) x, y+1, z; (v) -x, -y+1, -z+1.

Data collection: APEX2 (Bruker, 2009[Bruker (2009). APEX2, SAINT and SADABS. Bruker AXS Inc., Madison, Wisconsin, USA.]); cell refinement: SAINT (Bruker, 2009[Bruker (2009). APEX2, SAINT and SADABS. Bruker AXS Inc., Madison, Wisconsin, USA.]); data reduction: SAINT; program(s) used to solve structure: SHELXTL (Sheldrick, 2008[Sheldrick, G. M. (2008). Acta Cryst. A64, 112-122.]); program(s) used to refine structure: SHELXTL; molecular graphics: SHELXTL; software used to prepare material for publication: SHELXTL and PLATON (Spek, 2009[Spek, A. L. (2009). Acta Cryst. D65, 148-155.]).

Supporting information


Comment top

Synthesis of xanthene derivatives is currently of great interest and has attracted considerable attention by chemists because of their biological and pharmaceutical properties as antiviral (Lambert et al., 1997), antibacterial (Hideo, 1981), and anti-inflammatory (Poupelin et al., 1978). Xanthenes derivatives also find use as dyes, fluorescent material for visualization of biomolecules and in laser technologies (Menchen et al., 2003; Banerjee & Mukherjee, 1981). Several natural occurring polycyclic compounds containing xanthene nucleus are also reported (Ravindranath & Seshadri, 1973). Synthesis of xanthene and 1,8-dioxooctahydroxanthene derivatives have been reported in literature under the different reaction conditions with or without the use of catalyst (Fan et al., 2005; Jin et al., 2005; Srihari et al., 2008). Here we are reporting the synthesis of title compound, (I). The structure of the title compound was established on the basis of its IR, 1H NMR, 13C NMR spectra and finally confirmed by X-ray analysis.

The asymmetric unit of (I) consists of two crystallographically independent molecules, A and B (Fig. 1). The geometric parameters and the conformations are very similar to the previously reported structure (Mehdi et al., 2011). However, only the dimethoxyphenyl of molecule B is different from others. The dimethoxyphenyl grouping in molecule A is almost planar [C20A–O4A–C17A–C18A = -1.9 (2)° and C21A–O5A–C16A–C17A = 4.6 (2)°] whereas for molecule B is not planar [C20B–O4B–C17B–C18B = -6.1 (2)° and C21B–O5B–C16B–C15B = -103.40 (16)°]. Similarly, the mean plane of pyran ring and the dimethoxyphenyl ring for both A and B molecules are nearly perpendicular to one another with the dihedral angles between them being 86.81 (8) and 84.45 (9)°, respectively. For both molecules, the two cyclohexane rings adopt envelope conformations whereas the pyran ring adopts a boat conformation (Cremer & Pople, 1975).

In the crystal, the molecules are linked into a three-dimensional network (Fig. 2) by C—H···O hydrogen bonds (Table 1).

Related literature top

For applications of xanthene derivatives, see: Lambert et al. (1997); Hideo (1981); Poupelin et al. (1978); Menchen et al. (2003); Banerjee & Mukherjee (1981); Ravindranath & Seshadri (1973). For the synthesis of xanthene and 1,8-dioxooctahydroxanthene derivatives with or without the use of a catalyst, see: Fan et al. (2005); Jin et al. (2005); Srihari et al. (2008). For a related structure, see: Mehdi et al. (2011). For the stability of the temperature controller used in the data collection, see: Cosier & Glazer (1986). For ring conformations, see: Cremer & Pople (1975).

Experimental top

A mixture of dimedone (1.40 g m, 10 mmol) and veratraldehyde (1.66 g m, 10 mmol) was heated in 25 ml of glacial acetic acid for three hours. Completion of the reaction was monitored by TLC. The reaction mixture was dried on rotary evaporator under reduced pressure. The crude mixture thus obtained was successively treated with di ethyl ether chloroform and ethanol. The ethanol fraction on crystallization furnished yellow blocks of (I) (m pt. 208 °C, Yield 90%). IR (KBr) νmax: 3085, 3005, 2956, 2929, 2870, 2822, 1667, 1624, 1515, 1467, 1419, 1358, 1227, 1141, 1105, 1023, 851, 830, 751 cm-1. 1H NMR (300 MHz, DMSO-d6): δ 6.75–6.92 (3H, m, Aromatic protons), 4.72 (1H, s), 3.83 (3H, s), 3.78 (3H, s), 2.40 (4H, s), 2.17 (4H, s), 1.05 (6H, s), 1.02 (6H, s). 13C NMR (75 MHz, DMSO-d6): δ 27.2, 36.8, 42.4, 52.2, 56.4, 112.2, 114.6, 115.2, 123.4, 136.8, 146.6, 148.4, 198.2. IR spectrum was taken on Shimadzu IR-408 Perkin Elmer 1800 (FTIR). 1H NMR was recorded on Bruker Avance 300 MHz with TMS as an internal standard and 75 MHz for 13C NMR. Spectrum was recorded in DMSO-d6. The melting point was taken on Thermo Fisher digital melting point apparatus of IA9000 series and is uncorrected.

Refinement top

All hydrogen atoms were positioned geomatrically [C–H = 0.95–1.00 Å] and refined using a riding model, with Uiso(H) = 1.2 or 1.5 Ueq(C). A rotating-group model were applied for methyl groups.

Computing details top

Data collection: APEX2 (Bruker, 2009); cell refinement: SAINT (Bruker, 2009); data reduction: SAINT (Bruker, 2009); program(s) used to solve structure: SHELXTL (Sheldrick, 2008); program(s) used to refine structure: SHELXTL (Sheldrick, 2008); molecular graphics: SHELXTL (Sheldrick, 2008); software used to prepare material for publication: SHELXTL (Sheldrick, 2008) and PLATON (Spek, 2009).

Figures top
[Figure 1] Fig. 1. The molecular structure of (I) with 50% probability ellipsoids for non-H atoms.
[Figure 2] Fig. 2. The packing of (I), viewed down b axis, showing molecules linked into a three-dimensional network. Hydrogen bonds are shown as dashed lines.
9-(3,4-Dimethoxyphenyl)-3,3,6,6-tetramethyl-4,5,6,9-tetrahydro- 3H-xanthene-1,8(2H,7H)-dione top
Crystal data top
C25H30O5Z = 4
Mr = 410.49F(000) = 880
Triclinic, P1Dx = 1.255 Mg m3
Hall symbol: -P 1Mo Kα radiation, λ = 0.71073 Å
a = 9.4895 (7) ÅCell parameters from 9984 reflections
b = 10.2283 (7) Åθ = 2.2–30.0°
c = 23.3218 (16) ŵ = 0.09 mm1
α = 85.872 (4)°T = 100 K
β = 86.537 (4)°Block, yellow
γ = 74.425 (3)°0.42 × 0.39 × 0.20 mm
V = 2172.9 (3) Å3
Data collection top
Bruker SMART APEXII CCD
diffractometer
11497 independent reflections
Radiation source: fine-focus sealed tube8871 reflections with I > 2σ(I)
Graphite monochromatorRint = 0.040
ϕ and ω scansθmax = 29.0°, θmin = 0.9°
Absorption correction: multi-scan
(SADABS; Bruker, 2009)
h = 1212
Tmin = 0.965, Tmax = 0.983k = 1313
44431 measured reflectionsl = 3131
Refinement top
Refinement on F2Primary atom site location: structure-invariant direct methods
Least-squares matrix: fullSecondary atom site location: difference Fourier map
R[F2 > 2σ(F2)] = 0.054Hydrogen site location: inferred from neighbouring sites
wR(F2) = 0.127H-atom parameters constrained
S = 1.01 w = 1/[σ2(Fo2) + (0.0552P)2 + 1.1161P]
where P = (Fo2 + 2Fc2)/3
11497 reflections(Δ/σ)max = 0.001
553 parametersΔρmax = 0.42 e Å3
0 restraintsΔρmin = 0.28 e Å3
Crystal data top
C25H30O5γ = 74.425 (3)°
Mr = 410.49V = 2172.9 (3) Å3
Triclinic, P1Z = 4
a = 9.4895 (7) ÅMo Kα radiation
b = 10.2283 (7) ŵ = 0.09 mm1
c = 23.3218 (16) ÅT = 100 K
α = 85.872 (4)°0.42 × 0.39 × 0.20 mm
β = 86.537 (4)°
Data collection top
Bruker SMART APEXII CCD
diffractometer
11497 independent reflections
Absorption correction: multi-scan
(SADABS; Bruker, 2009)
8871 reflections with I > 2σ(I)
Tmin = 0.965, Tmax = 0.983Rint = 0.040
44431 measured reflections
Refinement top
R[F2 > 2σ(F2)] = 0.0540 restraints
wR(F2) = 0.127H-atom parameters constrained
S = 1.01Δρmax = 0.42 e Å3
11497 reflectionsΔρmin = 0.28 e Å3
553 parameters
Special details top

Experimental. The crystal was placed in the cold stream of an Oxford Cryosystems Cobra open-flow nitrogen cryostat (Cosier & Glazer, 1986) operating at 100.0 (1) K.

Geometry. All e.s.d.'s (except the e.s.d. in the dihedral angle between two l.s. planes) are estimated using the full covariance matrix. The cell e.s.d.'s are taken into account individually in the estimation of e.s.d.'s in distances, angles and torsion angles; correlations between e.s.d.'s in cell parameters are only used when they are defined by crystal symmetry. An approximate (isotropic) treatment of cell e.s.d.'s is used for estimating e.s.d.'s involving l.s. planes.

Refinement. Refinement of F2 against ALL reflections. The weighted R-factor wR and goodness of fit S are based on F2, conventional R-factors R are based on F, with F set to zero for negative F2. The threshold expression of F2 > σ(F2) is used only for calculating R-factors(gt) etc. and is not relevant to the choice of reflections for refinement. R-factors based on F2 are statistically about twice as large as those based on F, and R- factors based on ALL data will be even larger.

Fractional atomic coordinates and isotropic or equivalent isotropic displacement parameters (Å2) top
xyzUiso*/Ueq
O1A0.51121 (11)0.01893 (10)0.13242 (4)0.0167 (2)
O2A0.30935 (12)0.27866 (12)0.03360 (5)0.0222 (2)
O3A0.00427 (11)0.10581 (11)0.13190 (5)0.0194 (2)
O4A0.03071 (11)0.72025 (10)0.14408 (5)0.0170 (2)
O5A0.26685 (12)0.56744 (11)0.18780 (5)0.0212 (2)
C1A0.39692 (15)0.15892 (14)0.05242 (6)0.0130 (3)
C2A0.41570 (16)0.22544 (14)0.00480 (6)0.0146 (3)
C3A0.56930 (16)0.22129 (15)0.02765 (6)0.0163 (3)
H3AA0.56620.30590.05160.020*
H3AB0.60340.14420.05290.020*
C4A0.68098 (16)0.20643 (15)0.01876 (6)0.0156 (3)
C5A0.67052 (16)0.08554 (15)0.06052 (6)0.0153 (3)
H5AA0.71320.00020.04120.018*
H5AB0.72890.08470.09440.018*
C6A0.51680 (16)0.09159 (14)0.08028 (6)0.0137 (3)
C7A0.37572 (16)0.00791 (14)0.15400 (6)0.0147 (3)
C8A0.38861 (16)0.08773 (15)0.20637 (6)0.0176 (3)
H8AA0.47370.08310.22800.021*
H8AB0.40640.18180.19430.021*
C9A0.24950 (16)0.05339 (15)0.24603 (6)0.0167 (3)
C10A0.11824 (17)0.04029 (15)0.20912 (6)0.0173 (3)
H10A0.11950.13200.19770.021*
H10B0.02760.00670.23300.021*
C11A0.11168 (16)0.05299 (14)0.15528 (6)0.0150 (3)
C12A0.25000 (16)0.07503 (14)0.12990 (6)0.0133 (3)
C13A0.24385 (15)0.17523 (14)0.07831 (6)0.0129 (3)
H13A0.18110.15490.04900.015*
C14A0.18013 (15)0.32153 (14)0.09553 (6)0.0132 (3)
C15A0.25380 (16)0.37360 (14)0.13478 (6)0.0151 (3)
H15A0.34020.31700.15110.018*
C16A0.20193 (16)0.50682 (15)0.15011 (6)0.0150 (3)
C17A0.07316 (15)0.59013 (14)0.12625 (6)0.0140 (3)
C18A0.00021 (16)0.53859 (14)0.08766 (6)0.0151 (3)
H18A0.08730.59450.07160.018*
C19A0.05405 (15)0.40429 (14)0.07237 (6)0.0143 (3)
H19A0.00370.36940.04570.017*
C20A0.09712 (16)0.80929 (15)0.11921 (7)0.0169 (3)
H20A0.11430.90000.13370.025*
H20B0.18200.77380.12960.025*
H20C0.08250.81500.07720.025*
C21A0.4031 (2)0.48823 (19)0.20905 (9)0.0326 (4)
H21A0.43980.54140.23510.049*
H21B0.47400.46310.17670.049*
H21C0.38910.40570.23000.049*
C22A0.65038 (18)0.33737 (16)0.05122 (7)0.0223 (3)
H22A0.66080.41270.02440.033*
H22B0.72030.32490.08170.033*
H22C0.55050.35800.06830.033*
C23A0.83548 (17)0.17712 (16)0.00895 (7)0.0203 (3)
H23A0.84390.25420.03520.031*
H23B0.85480.09490.03050.031*
H23C0.90680.16340.02110.031*
C24A0.23732 (19)0.07937 (17)0.27513 (7)0.0244 (3)
H24A0.14890.10000.30040.037*
H24B0.23170.15370.24570.037*
H24C0.32360.06920.29790.037*
C25A0.25761 (18)0.16875 (17)0.29255 (7)0.0235 (3)
H25A0.17100.14560.31880.035*
H25B0.34600.18130.31420.035*
H25C0.26100.25310.27440.035*
O1B0.06753 (11)0.41491 (11)0.63022 (4)0.0175 (2)
O2B0.17623 (12)0.22238 (12)0.46132 (5)0.0258 (3)
O3B0.43753 (12)0.39314 (12)0.61832 (5)0.0246 (3)
O4B0.48890 (11)0.23710 (10)0.66652 (5)0.0195 (2)
O5B0.23066 (11)0.09300 (11)0.71319 (4)0.0182 (2)
C1B0.06703 (16)0.30810 (15)0.54858 (6)0.0156 (3)
C2B0.06302 (17)0.26311 (15)0.49034 (6)0.0177 (3)
C3B0.08492 (17)0.27615 (16)0.46638 (6)0.0195 (3)
H3BA0.07500.20270.43980.023*
H3BB0.11440.36380.44360.023*
C4B0.20776 (16)0.26930 (15)0.51161 (6)0.0167 (3)
C5B0.20940 (16)0.37152 (15)0.55704 (6)0.0173 (3)
H5BA0.25120.46480.54050.021*
H5BB0.27360.35550.59040.021*
C6B0.06074 (16)0.36086 (15)0.57727 (6)0.0157 (3)
C7B0.05787 (16)0.44058 (15)0.64789 (6)0.0160 (3)
C8B0.02695 (17)0.52491 (16)0.69919 (7)0.0187 (3)
H8BA0.04260.49240.72620.022*
H8BB0.02010.62050.68670.022*
C9B0.16583 (17)0.51902 (15)0.73048 (6)0.0180 (3)
C10B0.28224 (17)0.54196 (16)0.68493 (7)0.0195 (3)
H10C0.24760.63390.66590.023*
H10D0.37360.53790.70420.023*
C11B0.31460 (16)0.43762 (16)0.63990 (7)0.0185 (3)
C12B0.18952 (16)0.39419 (14)0.62110 (6)0.0158 (3)
C13B0.21341 (16)0.29660 (15)0.57359 (6)0.0156 (3)
H13B0.27890.32480.54270.019*
C14B0.28762 (16)0.15174 (15)0.59614 (6)0.0153 (3)
C15B0.22690 (16)0.09184 (15)0.64401 (6)0.0165 (3)
H15B0.13660.14050.66130.020*
C16B0.29577 (16)0.03643 (15)0.66644 (6)0.0154 (3)
C17B0.42943 (16)0.11082 (15)0.64140 (6)0.0150 (3)
C18B0.49040 (16)0.05217 (15)0.59372 (6)0.0163 (3)
H18B0.58050.10070.57630.020*
C19B0.41944 (16)0.07738 (15)0.57161 (6)0.0164 (3)
H19B0.46210.11590.53900.020*
C20B0.61663 (17)0.31935 (16)0.63789 (7)0.0215 (3)
H20D0.64440.40980.65770.032*
H20E0.69740.27660.63850.032*
H20F0.59540.32780.59790.032*
C21B0.29838 (18)0.08858 (17)0.76608 (7)0.0221 (3)
H21D0.24590.12560.79790.033*
H21E0.29500.00580.77270.033*
H21F0.40060.14290.76380.033*
C22B0.18128 (19)0.12487 (16)0.53976 (7)0.0226 (3)
H22D0.18200.06120.51040.034*
H22E0.25880.12230.56920.034*
H22F0.08610.09890.55760.034*
C23B0.35524 (18)0.30927 (17)0.48314 (7)0.0227 (3)
H23D0.35620.24360.45470.034*
H23E0.37040.40020.46400.034*
H23G0.43380.30980.51250.034*
C24B0.22219 (19)0.37987 (17)0.76248 (7)0.0246 (4)
H24D0.14520.36230.78950.037*
H24G0.30830.37950.78380.037*
H24E0.24910.30890.73470.037*
C25B0.13179 (19)0.63007 (17)0.77360 (7)0.0226 (3)
H25D0.05220.61800.80050.034*
H25E0.10200.71940.75300.034*
H25F0.21930.62410.79500.034*
Atomic displacement parameters (Å2) top
U11U22U33U12U13U23
O1A0.0117 (5)0.0192 (5)0.0173 (5)0.0019 (4)0.0001 (4)0.0038 (4)
O2A0.0161 (5)0.0282 (6)0.0198 (5)0.0020 (4)0.0034 (4)0.0031 (5)
O3A0.0142 (5)0.0211 (5)0.0228 (5)0.0046 (4)0.0010 (4)0.0011 (4)
O4A0.0151 (5)0.0109 (5)0.0230 (5)0.0012 (4)0.0043 (4)0.0027 (4)
O5A0.0169 (5)0.0177 (5)0.0284 (6)0.0006 (4)0.0105 (5)0.0084 (5)
C1A0.0122 (7)0.0116 (6)0.0153 (7)0.0027 (5)0.0003 (5)0.0035 (5)
C2A0.0158 (7)0.0120 (6)0.0157 (7)0.0026 (5)0.0010 (6)0.0036 (5)
C3A0.0155 (7)0.0180 (7)0.0140 (7)0.0027 (5)0.0004 (5)0.0003 (6)
C4A0.0137 (7)0.0157 (7)0.0168 (7)0.0035 (5)0.0008 (5)0.0004 (5)
C5A0.0125 (7)0.0148 (7)0.0166 (7)0.0005 (5)0.0002 (5)0.0002 (5)
C6A0.0147 (7)0.0117 (6)0.0145 (6)0.0029 (5)0.0002 (5)0.0016 (5)
C7A0.0140 (7)0.0136 (7)0.0166 (7)0.0036 (5)0.0015 (5)0.0026 (5)
C8A0.0159 (7)0.0159 (7)0.0186 (7)0.0013 (5)0.0004 (6)0.0021 (6)
C9A0.0178 (7)0.0170 (7)0.0150 (7)0.0047 (6)0.0019 (6)0.0015 (6)
C10A0.0183 (7)0.0172 (7)0.0176 (7)0.0072 (6)0.0021 (6)0.0021 (6)
C11A0.0156 (7)0.0138 (7)0.0164 (7)0.0042 (5)0.0002 (6)0.0051 (5)
C12A0.0144 (7)0.0107 (6)0.0148 (6)0.0028 (5)0.0005 (5)0.0031 (5)
C13A0.0111 (6)0.0119 (6)0.0148 (6)0.0011 (5)0.0009 (5)0.0019 (5)
C14A0.0117 (7)0.0132 (6)0.0140 (6)0.0023 (5)0.0014 (5)0.0005 (5)
C15A0.0118 (7)0.0146 (7)0.0173 (7)0.0005 (5)0.0022 (5)0.0005 (5)
C16A0.0134 (7)0.0155 (7)0.0159 (7)0.0031 (5)0.0015 (5)0.0022 (5)
C17A0.0125 (7)0.0121 (6)0.0162 (7)0.0017 (5)0.0009 (5)0.0000 (5)
C18A0.0121 (7)0.0139 (7)0.0174 (7)0.0003 (5)0.0015 (5)0.0007 (5)
C19A0.0123 (7)0.0155 (7)0.0153 (7)0.0036 (5)0.0014 (5)0.0023 (5)
C20A0.0130 (7)0.0129 (7)0.0219 (7)0.0016 (5)0.0030 (6)0.0001 (6)
C21A0.0249 (9)0.0268 (9)0.0440 (11)0.0035 (7)0.0212 (8)0.0127 (8)
C22A0.0210 (8)0.0189 (8)0.0279 (8)0.0064 (6)0.0011 (7)0.0056 (6)
C23A0.0152 (7)0.0239 (8)0.0215 (8)0.0056 (6)0.0026 (6)0.0004 (6)
C24A0.0281 (9)0.0249 (8)0.0209 (8)0.0067 (7)0.0017 (7)0.0075 (6)
C25A0.0228 (8)0.0261 (8)0.0203 (8)0.0062 (6)0.0020 (6)0.0033 (6)
O1B0.0123 (5)0.0217 (5)0.0192 (5)0.0047 (4)0.0028 (4)0.0084 (4)
O2B0.0199 (6)0.0333 (7)0.0213 (6)0.0025 (5)0.0077 (5)0.0068 (5)
O3B0.0141 (5)0.0300 (6)0.0296 (6)0.0065 (5)0.0039 (5)0.0022 (5)
O4B0.0171 (5)0.0149 (5)0.0229 (5)0.0007 (4)0.0059 (4)0.0018 (4)
O5B0.0169 (5)0.0196 (5)0.0184 (5)0.0065 (4)0.0052 (4)0.0013 (4)
C1B0.0147 (7)0.0142 (7)0.0171 (7)0.0026 (5)0.0014 (6)0.0010 (5)
C2B0.0197 (7)0.0156 (7)0.0163 (7)0.0032 (6)0.0036 (6)0.0003 (6)
C3B0.0215 (8)0.0205 (7)0.0152 (7)0.0035 (6)0.0005 (6)0.0016 (6)
C4B0.0169 (7)0.0176 (7)0.0161 (7)0.0050 (6)0.0010 (6)0.0039 (6)
C5B0.0141 (7)0.0180 (7)0.0190 (7)0.0027 (5)0.0015 (6)0.0046 (6)
C6B0.0158 (7)0.0160 (7)0.0154 (7)0.0042 (5)0.0003 (6)0.0024 (5)
C7B0.0139 (7)0.0152 (7)0.0192 (7)0.0042 (5)0.0004 (6)0.0016 (6)
C8B0.0164 (7)0.0185 (7)0.0213 (7)0.0043 (6)0.0018 (6)0.0058 (6)
C9B0.0183 (7)0.0189 (7)0.0174 (7)0.0062 (6)0.0015 (6)0.0019 (6)
C10B0.0177 (7)0.0223 (8)0.0212 (7)0.0103 (6)0.0015 (6)0.0003 (6)
C11B0.0157 (7)0.0199 (7)0.0195 (7)0.0054 (6)0.0000 (6)0.0044 (6)
C12B0.0157 (7)0.0138 (7)0.0169 (7)0.0027 (5)0.0004 (6)0.0005 (5)
C13B0.0113 (7)0.0169 (7)0.0176 (7)0.0028 (5)0.0043 (5)0.0011 (6)
C14B0.0122 (7)0.0164 (7)0.0177 (7)0.0037 (5)0.0007 (5)0.0041 (6)
C15B0.0113 (7)0.0184 (7)0.0191 (7)0.0030 (5)0.0047 (6)0.0047 (6)
C16B0.0134 (7)0.0179 (7)0.0161 (7)0.0066 (5)0.0034 (5)0.0034 (6)
C17B0.0117 (7)0.0162 (7)0.0178 (7)0.0040 (5)0.0005 (5)0.0047 (6)
C18B0.0116 (7)0.0194 (7)0.0174 (7)0.0028 (5)0.0037 (5)0.0068 (6)
C19B0.0143 (7)0.0191 (7)0.0156 (7)0.0046 (6)0.0035 (6)0.0030 (6)
C20B0.0174 (8)0.0180 (7)0.0254 (8)0.0016 (6)0.0036 (6)0.0052 (6)
C21B0.0216 (8)0.0251 (8)0.0196 (7)0.0067 (6)0.0037 (6)0.0024 (6)
C22B0.0246 (8)0.0186 (8)0.0256 (8)0.0075 (6)0.0003 (7)0.0016 (6)
C23B0.0199 (8)0.0283 (9)0.0210 (8)0.0070 (6)0.0019 (6)0.0054 (7)
C24B0.0256 (9)0.0243 (8)0.0211 (8)0.0036 (7)0.0016 (7)0.0028 (6)
C25B0.0243 (8)0.0249 (8)0.0211 (8)0.0100 (7)0.0022 (6)0.0045 (6)
Geometric parameters (Å, º) top
O1A—C7A1.3822 (17)O1B—C7B1.3774 (18)
O1A—C6A1.3847 (16)O1B—C6B1.3800 (18)
O2A—C2A1.2248 (18)O2B—C2B1.2240 (18)
O3A—C11A1.2291 (18)O3B—C11B1.2240 (18)
O4A—C17A1.3704 (17)O4B—C17B1.3673 (17)
O4A—C20A1.4329 (17)O4B—C20B1.4346 (17)
O5A—C16A1.3733 (18)O5B—C16B1.3875 (16)
O5A—C21A1.4247 (19)O5B—C21B1.434 (2)
C1A—C6A1.340 (2)C1B—C6B1.346 (2)
C1A—C2A1.4768 (19)C1B—C2B1.471 (2)
C1A—C13A1.5102 (19)C1B—C13B1.511 (2)
C2A—C3A1.512 (2)C2B—C3B1.512 (2)
C3A—C4A1.532 (2)C3B—C4B1.537 (2)
C3A—H3AA0.9900C3B—H3BA0.9900
C3A—H3AB0.9900C3B—H3BB0.9900
C4A—C23A1.528 (2)C4B—C23B1.527 (2)
C4A—C22A1.537 (2)C4B—C22B1.535 (2)
C4A—C5A1.5390 (19)C4B—C5B1.538 (2)
C5A—C6A1.489 (2)C5B—C6B1.488 (2)
C5A—H5AA0.9900C5B—H5BA0.9900
C5A—H5AB0.9900C5B—H5BB0.9900
C7A—C12A1.340 (2)C7B—C12B1.344 (2)
C7A—C8A1.4983 (19)C7B—C8B1.494 (2)
C8A—C9A1.540 (2)C8B—C9B1.530 (2)
C8A—H8AA0.9900C8B—H8BA0.9900
C8A—H8AB0.9900C8B—H8BB0.9900
C9A—C10A1.528 (2)C9B—C25B1.528 (2)
C9A—C25A1.534 (2)C9B—C24B1.535 (2)
C9A—C24A1.535 (2)C9B—C10B1.538 (2)
C10A—C11A1.515 (2)C10B—C11B1.511 (2)
C10A—H10A0.9900C10B—H10C0.9900
C10A—H10B0.9900C10B—H10D0.9900
C11A—C12A1.4730 (19)C11B—C12B1.474 (2)
C12A—C13A1.5167 (19)C12B—C13B1.511 (2)
C13A—C14A1.5289 (19)C13B—C14B1.530 (2)
C13A—H13A1.0000C13B—H13B1.0000
C14A—C19A1.3813 (19)C14B—C19B1.391 (2)
C14A—C15A1.399 (2)C14B—C15B1.4026 (19)
C15A—C16A1.384 (2)C15B—C16B1.380 (2)
C15A—H15A0.9500C15B—H15B0.9500
C16A—C17A1.408 (2)C16B—C17B1.4090 (19)
C17A—C18A1.383 (2)C17B—C18B1.394 (2)
C18A—C19A1.396 (2)C18B—C19B1.393 (2)
C18A—H18A0.9500C18B—H18B0.9500
C19A—H19A0.9500C19B—H19B0.9500
C20A—H20A0.9800C20B—H20D0.9800
C20A—H20B0.9800C20B—H20E0.9800
C20A—H20C0.9800C20B—H20F0.9800
C21A—H21A0.9800C21B—H21D0.9800
C21A—H21B0.9800C21B—H21E0.9800
C21A—H21C0.9800C21B—H21F0.9800
C22A—H22A0.9800C22B—H22D0.9800
C22A—H22B0.9800C22B—H22E0.9800
C22A—H22C0.9800C22B—H22F0.9800
C23A—H23A0.9800C23B—H23D0.9800
C23A—H23B0.9800C23B—H23E0.9800
C23A—H23C0.9800C23B—H23G0.9800
C24A—H24A0.9800C24B—H24D0.9800
C24A—H24B0.9800C24B—H24G0.9800
C24A—H24C0.9800C24B—H24E0.9800
C25A—H25A0.9800C25B—H25D0.9800
C25A—H25B0.9800C25B—H25E0.9800
C25A—H25C0.9800C25B—H25F0.9800
C7A—O1A—C6A117.69 (11)C7B—O1B—C6B117.46 (11)
C17A—O4A—C20A116.72 (12)C17B—O4B—C20B116.61 (11)
C16A—O5A—C21A116.35 (12)C16B—O5B—C21B112.54 (11)
C6A—C1A—C2A118.52 (12)C6B—C1B—C2B118.46 (14)
C6A—C1A—C13A122.70 (12)C6B—C1B—C13B122.33 (14)
C2A—C1A—C13A118.71 (12)C2B—C1B—C13B119.20 (12)
O2A—C2A—C1A120.48 (13)O2B—C2B—C1B120.67 (14)
O2A—C2A—C3A121.12 (13)O2B—C2B—C3B121.21 (14)
C1A—C2A—C3A118.36 (12)C1B—C2B—C3B118.04 (13)
C2A—C3A—C4A114.67 (12)C2B—C3B—C4B115.09 (12)
C2A—C3A—H3AA108.6C2B—C3B—H3BA108.5
C4A—C3A—H3AA108.6C4B—C3B—H3BA108.5
C2A—C3A—H3AB108.6C2B—C3B—H3BB108.5
C4A—C3A—H3AB108.6C4B—C3B—H3BB108.5
H3AA—C3A—H3AB107.6H3BA—C3B—H3BB107.5
C23A—C4A—C3A109.81 (12)C23B—C4B—C22B109.54 (13)
C23A—C4A—C22A109.05 (13)C23B—C4B—C3B109.74 (12)
C3A—C4A—C22A110.56 (12)C22B—C4B—C3B110.21 (12)
C23A—C4A—C5A108.77 (12)C23B—C4B—C5B108.79 (12)
C3A—C4A—C5A108.24 (12)C22B—C4B—C5B110.42 (12)
C22A—C4A—C5A110.40 (12)C3B—C4B—C5B108.10 (12)
C6A—C5A—C4A112.43 (12)C6B—C5B—C4B112.54 (12)
C6A—C5A—H5AA109.1C6B—C5B—H5BA109.1
C4A—C5A—H5AA109.1C4B—C5B—H5BA109.1
C6A—C5A—H5AB109.1C6B—C5B—H5BB109.1
C4A—C5A—H5AB109.1C4B—C5B—H5BB109.1
H5AA—C5A—H5AB107.9H5BA—C5B—H5BB107.8
C1A—C6A—O1A123.02 (12)C1B—C6B—O1B122.38 (14)
C1A—C6A—C5A125.53 (12)C1B—C6B—C5B126.03 (14)
O1A—C6A—C5A111.45 (12)O1B—C6B—C5B111.58 (12)
C12A—C7A—O1A123.02 (12)C12B—C7B—O1B122.74 (14)
C12A—C7A—C8A125.29 (13)C12B—C7B—C8B125.82 (14)
O1A—C7A—C8A111.68 (12)O1B—C7B—C8B111.44 (12)
C7A—C8A—C9A111.83 (12)C7B—C8B—C9B112.29 (12)
C7A—C8A—H8AA109.3C7B—C8B—H8BA109.1
C9A—C8A—H8AA109.3C9B—C8B—H8BA109.1
C7A—C8A—H8AB109.3C7B—C8B—H8BB109.1
C9A—C8A—H8AB109.3C9B—C8B—H8BB109.1
H8AA—C8A—H8AB107.9H8BA—C8B—H8BB107.9
C10A—C9A—C25A109.77 (13)C25B—C9B—C8B109.18 (13)
C10A—C9A—C24A110.97 (13)C25B—C9B—C24B109.33 (13)
C25A—C9A—C24A108.99 (13)C8B—C9B—C24B110.65 (13)
C10A—C9A—C8A107.73 (12)C25B—C9B—C10B110.53 (13)
C25A—C9A—C8A109.27 (12)C8B—C9B—C10B107.64 (12)
C24A—C9A—C8A110.09 (13)C24B—C9B—C10B109.49 (13)
C11A—C10A—C9A115.36 (12)C11B—C10B—C9B112.29 (12)
C11A—C10A—H10A108.4C11B—C10B—H10C109.1
C9A—C10A—H10A108.4C9B—C10B—H10C109.1
C11A—C10A—H10B108.4C11B—C10B—H10D109.1
C9A—C10A—H10B108.4C9B—C10B—H10D109.1
H10A—C10A—H10B107.5H10C—C10B—H10D107.9
O3A—C11A—C12A120.24 (13)O3B—C11B—C12B120.67 (15)
O3A—C11A—C10A121.64 (13)O3B—C11B—C10B122.39 (14)
C12A—C11A—C10A118.08 (13)C12B—C11B—C10B116.91 (13)
C7A—C12A—C11A118.74 (12)C7B—C12B—C11B118.63 (14)
C7A—C12A—C13A122.70 (13)C7B—C12B—C13B122.00 (14)
C11A—C12A—C13A118.55 (12)C11B—C12B—C13B119.35 (13)
C1A—C13A—C12A108.84 (11)C12B—C13B—C1B108.13 (12)
C1A—C13A—C14A109.54 (11)C12B—C13B—C14B110.72 (12)
C12A—C13A—C14A111.20 (11)C1B—C13B—C14B112.55 (12)
C1A—C13A—H13A109.1C12B—C13B—H13B108.4
C12A—C13A—H13A109.1C1B—C13B—H13B108.4
C14A—C13A—H13A109.1C14B—C13B—H13B108.4
C19A—C14A—C15A119.31 (13)C19B—C14B—C15B117.90 (13)
C19A—C14A—C13A121.78 (13)C19B—C14B—C13B121.54 (13)
C15A—C14A—C13A118.89 (12)C15B—C14B—C13B120.51 (12)
C16A—C15A—C14A120.59 (13)C16B—C15B—C14B121.26 (13)
C16A—C15A—H15A119.7C16B—C15B—H15B119.4
C14A—C15A—H15A119.7C14B—C15B—H15B119.4
O5A—C16A—C15A124.95 (13)C15B—C16B—O5B119.43 (13)
O5A—C16A—C17A115.49 (13)C15B—C16B—C17B120.43 (13)
C15A—C16A—C17A119.56 (14)O5B—C16B—C17B120.12 (13)
O4A—C17A—C18A124.90 (13)O4B—C17B—C18B125.18 (13)
O4A—C17A—C16A115.18 (13)O4B—C17B—C16B116.13 (12)
C18A—C17A—C16A119.91 (13)C18B—C17B—C16B118.69 (13)
C17A—C18A—C19A119.82 (13)C19B—C18B—C17B120.14 (13)
C17A—C18A—H18A120.1C19B—C18B—H18B119.9
C19A—C18A—H18A120.1C17B—C18B—H18B119.9
C14A—C19A—C18A120.80 (14)C14B—C19B—C18B121.58 (13)
C14A—C19A—H19A119.6C14B—C19B—H19B119.2
C18A—C19A—H19A119.6C18B—C19B—H19B119.2
O4A—C20A—H20A109.5O4B—C20B—H20D109.5
O4A—C20A—H20B109.5O4B—C20B—H20E109.5
H20A—C20A—H20B109.5H20D—C20B—H20E109.5
O4A—C20A—H20C109.5O4B—C20B—H20F109.5
H20A—C20A—H20C109.5H20D—C20B—H20F109.5
H20B—C20A—H20C109.5H20E—C20B—H20F109.5
O5A—C21A—H21A109.5O5B—C21B—H21D109.5
O5A—C21A—H21B109.5O5B—C21B—H21E109.5
H21A—C21A—H21B109.5H21D—C21B—H21E109.5
O5A—C21A—H21C109.5O5B—C21B—H21F109.5
H21A—C21A—H21C109.5H21D—C21B—H21F109.5
H21B—C21A—H21C109.5H21E—C21B—H21F109.5
C4A—C22A—H22A109.5C4B—C22B—H22D109.5
C4A—C22A—H22B109.5C4B—C22B—H22E109.5
H22A—C22A—H22B109.5H22D—C22B—H22E109.5
C4A—C22A—H22C109.5C4B—C22B—H22F109.5
H22A—C22A—H22C109.5H22D—C22B—H22F109.5
H22B—C22A—H22C109.5H22E—C22B—H22F109.5
C4A—C23A—H23A109.5C4B—C23B—H23D109.5
C4A—C23A—H23B109.5C4B—C23B—H23E109.5
H23A—C23A—H23B109.5H23D—C23B—H23E109.5
C4A—C23A—H23C109.5C4B—C23B—H23G109.5
H23A—C23A—H23C109.5H23D—C23B—H23G109.5
H23B—C23A—H23C109.5H23E—C23B—H23G109.5
C9A—C24A—H24A109.5C9B—C24B—H24D109.5
C9A—C24A—H24B109.5C9B—C24B—H24G109.5
H24A—C24A—H24B109.5H24D—C24B—H24G109.5
C9A—C24A—H24C109.5C9B—C24B—H24E109.5
H24A—C24A—H24C109.5H24D—C24B—H24E109.5
H24B—C24A—H24C109.5H24G—C24B—H24E109.5
C9A—C25A—H25A109.5C9B—C25B—H25D109.5
C9A—C25A—H25B109.5C9B—C25B—H25E109.5
H25A—C25A—H25B109.5H25D—C25B—H25E109.5
C9A—C25A—H25C109.5C9B—C25B—H25F109.5
H25A—C25A—H25C109.5H25D—C25B—H25F109.5
H25B—C25A—H25C109.5H25E—C25B—H25F109.5
C6A—C1A—C2A—O2A174.17 (14)C6B—C1B—C2B—O2B175.45 (14)
C13A—C1A—C2A—O2A8.7 (2)C13B—C1B—C2B—O2B3.2 (2)
C6A—C1A—C2A—C3A3.5 (2)C6B—C1B—C2B—C3B1.2 (2)
C13A—C1A—C2A—C3A173.59 (13)C13B—C1B—C2B—C3B179.85 (13)
O2A—C2A—C3A—C4A156.42 (14)O2B—C2B—C3B—C4B155.50 (14)
C1A—C2A—C3A—C4A25.91 (19)C1B—C2B—C3B—C4B27.87 (19)
C2A—C3A—C4A—C23A169.58 (12)C2B—C3B—C4B—C23B169.74 (13)
C2A—C3A—C4A—C22A70.06 (16)C2B—C3B—C4B—C22B69.55 (17)
C2A—C3A—C4A—C5A50.97 (16)C2B—C3B—C4B—C5B51.22 (17)
C23A—C4A—C5A—C6A168.10 (13)C23B—C4B—C5B—C6B166.56 (12)
C3A—C4A—C5A—C6A48.84 (16)C22B—C4B—C5B—C6B73.19 (16)
C22A—C4A—C5A—C6A72.29 (16)C3B—C4B—C5B—C6B47.44 (16)
C2A—C1A—C6A—O1A175.93 (13)C2B—C1B—C6B—O1B175.04 (13)
C13A—C1A—C6A—O1A7.1 (2)C13B—C1B—C6B—O1B3.6 (2)
C2A—C1A—C6A—C5A4.7 (2)C2B—C1B—C6B—C5B3.8 (2)
C13A—C1A—C6A—C5A172.24 (13)C13B—C1B—C6B—C5B177.60 (14)
C7A—O1A—C6A—C1A5.0 (2)C7B—O1B—C6B—C1B13.7 (2)
C7A—O1A—C6A—C5A175.62 (12)C7B—O1B—C6B—C5B165.29 (12)
C4A—C5A—C6A—C1A23.1 (2)C4B—C5B—C6B—C1B22.4 (2)
C4A—C5A—C6A—O1A156.26 (12)C4B—C5B—C6B—O1B158.66 (12)
C6A—O1A—C7A—C12A6.9 (2)C6B—O1B—C7B—C12B11.9 (2)
C6A—O1A—C7A—C8A172.65 (12)C6B—O1B—C7B—C8B167.92 (12)
C12A—C7A—C8A—C9A27.0 (2)C12B—C7B—C8B—C9B17.6 (2)
O1A—C7A—C8A—C9A153.46 (12)O1B—C7B—C8B—C9B162.62 (12)
C7A—C8A—C9A—C10A50.47 (16)C7B—C8B—C9B—C25B167.61 (12)
C7A—C8A—C9A—C25A169.68 (13)C7B—C8B—C9B—C24B72.01 (16)
C7A—C8A—C9A—C24A70.65 (16)C7B—C8B—C9B—C10B47.59 (16)
C25A—C9A—C10A—C11A169.89 (13)C25B—C9B—C10B—C11B177.59 (13)
C24A—C9A—C10A—C11A69.58 (16)C8B—C9B—C10B—C11B58.43 (16)
C8A—C9A—C10A—C11A51.00 (16)C24B—C9B—C10B—C11B61.91 (17)
C9A—C10A—C11A—O3A156.99 (14)C9B—C10B—C11B—O3B144.04 (15)
C9A—C10A—C11A—C12A25.40 (19)C9B—C10B—C11B—C12B38.10 (18)
O1A—C7A—C12A—C11A178.17 (13)O1B—C7B—C12B—C11B174.40 (12)
C8A—C7A—C12A—C11A1.3 (2)C8B—C7B—C12B—C11B5.4 (2)
O1A—C7A—C12A—C13A3.2 (2)O1B—C7B—C12B—C13B7.2 (2)
C8A—C7A—C12A—C13A177.30 (14)C8B—C7B—C12B—C13B173.05 (13)
O3A—C11A—C12A—C7A175.04 (14)O3B—C11B—C12B—C7B176.85 (14)
C10A—C11A—C12A—C7A2.6 (2)C10B—C11B—C12B—C7B5.3 (2)
O3A—C11A—C12A—C13A6.3 (2)O3B—C11B—C12B—C13B1.6 (2)
C10A—C11A—C12A—C13A176.08 (13)C10B—C11B—C12B—C13B176.29 (12)
C6A—C1A—C13A—C12A15.15 (19)C7B—C12B—C13B—C1B21.57 (18)
C2A—C1A—C13A—C12A167.88 (12)C11B—C12B—C13B—C1B160.03 (12)
C6A—C1A—C13A—C14A106.62 (15)C7B—C12B—C13B—C14B102.17 (16)
C2A—C1A—C13A—C14A70.35 (16)C11B—C12B—C13B—C14B76.23 (16)
C7A—C12A—C13A—C1A13.27 (19)C6B—C1B—C13B—C12B19.82 (19)
C11A—C12A—C13A—C1A168.10 (12)C2B—C1B—C13B—C12B158.77 (12)
C7A—C12A—C13A—C14A107.48 (16)C6B—C1B—C13B—C14B102.80 (16)
C11A—C12A—C13A—C14A71.14 (16)C2B—C1B—C13B—C14B78.61 (16)
C1A—C13A—C14A—C19A120.01 (14)C12B—C13B—C14B—C19B123.15 (15)
C12A—C13A—C14A—C19A119.65 (14)C1B—C13B—C14B—C19B115.69 (15)
C1A—C13A—C14A—C15A58.45 (16)C12B—C13B—C14B—C15B54.28 (18)
C12A—C13A—C14A—C15A61.90 (16)C1B—C13B—C14B—C15B66.88 (18)
C19A—C14A—C15A—C16A0.4 (2)C19B—C14B—C15B—C16B0.4 (2)
C13A—C14A—C15A—C16A178.06 (12)C13B—C14B—C15B—C16B177.13 (14)
C21A—O5A—C16A—C15A4.6 (2)C14B—C15B—C16B—O5B178.82 (14)
C21A—O5A—C16A—C17A175.41 (14)C14B—C15B—C16B—C17B0.2 (2)
C14A—C15A—C16A—O5A179.48 (13)C21B—O5B—C16B—C15B103.40 (16)
C14A—C15A—C16A—C17A0.5 (2)C21B—O5B—C16B—C17B78.01 (17)
C20A—O4A—C17A—C18A1.9 (2)C20B—O4B—C17B—C18B6.1 (2)
C20A—O4A—C17A—C16A177.96 (12)C20B—O4B—C17B—C16B173.68 (13)
O5A—C16A—C17A—O4A0.01 (18)C15B—C16B—C17B—O4B179.75 (14)
C15A—C16A—C17A—O4A179.99 (12)O5B—C16B—C17B—O4B1.2 (2)
O5A—C16A—C17A—C18A179.82 (13)C15B—C16B—C17B—C18B0.1 (2)
C15A—C16A—C17A—C18A0.2 (2)O5B—C16B—C17B—C18B178.66 (13)
O4A—C17A—C18A—C19A179.58 (13)O4B—C17B—C18B—C19B179.72 (14)
C16A—C17A—C18A—C19A0.2 (2)C16B—C17B—C18B—C19B0.1 (2)
C15A—C14A—C19A—C18A0.0 (2)C15B—C14B—C19B—C18B0.4 (2)
C13A—C14A—C19A—C18A178.43 (12)C13B—C14B—C19B—C18B177.09 (14)
C17A—C18A—C19A—C14A0.3 (2)C17B—C18B—C19B—C14B0.3 (2)
Hydrogen-bond geometry (Å, º) top
D—H···AD—HH···AD···AD—H···A
C10A—H10A···O4Ai0.992.383.2817 (19)152
C18A—H18A···O2Aii0.952.353.2943 (19)176
C18B—H18B···O2Biii0.952.453.4000 (19)175
C20A—H20A···O3Aiv0.982.593.4144 (19)142
C24B—H24D···O4Av0.982.483.453 (2)171
Symmetry codes: (i) x, y1, z; (ii) x, y+1, z; (iii) x+1, y, z+1; (iv) x, y+1, z; (v) x, y+1, z+1.

Experimental details

Crystal data
Chemical formulaC25H30O5
Mr410.49
Crystal system, space groupTriclinic, P1
Temperature (K)100
a, b, c (Å)9.4895 (7), 10.2283 (7), 23.3218 (16)
α, β, γ (°)85.872 (4), 86.537 (4), 74.425 (3)
V3)2172.9 (3)
Z4
Radiation typeMo Kα
µ (mm1)0.09
Crystal size (mm)0.42 × 0.39 × 0.20
Data collection
DiffractometerBruker SMART APEXII CCD
diffractometer
Absorption correctionMulti-scan
(SADABS; Bruker, 2009)
Tmin, Tmax0.965, 0.983
No. of measured, independent and
observed [I > 2σ(I)] reflections
44431, 11497, 8871
Rint0.040
(sin θ/λ)max1)0.682
Refinement
R[F2 > 2σ(F2)], wR(F2), S 0.054, 0.127, 1.01
No. of reflections11497
No. of parameters553
H-atom treatmentH-atom parameters constrained
Δρmax, Δρmin (e Å3)0.42, 0.28

Computer programs: APEX2 (Bruker, 2009), SAINT (Bruker, 2009), SHELXTL (Sheldrick, 2008) and PLATON (Spek, 2009).

Hydrogen-bond geometry (Å, º) top
D—H···AD—HH···AD···AD—H···A
C10A—H10A···O4Ai0.992.383.2817 (19)152
C18A—H18A···O2Aii0.952.353.2943 (19)176
C18B—H18B···O2Biii0.952.453.4000 (19)175
C20A—H20A···O3Aiv0.982.593.4144 (19)142
C24B—H24D···O4Av0.982.483.453 (2)171
Symmetry codes: (i) x, y1, z; (ii) x, y+1, z; (iii) x+1, y, z+1; (iv) x, y+1, z; (v) x, y+1, z+1.
 

Footnotes

Thomson Reuters ResearcherID: A-5523-2009.

§Thomson Reuters ResearcherID: A-3561-2009.

Acknowledgements

SHM, OS and RMG would like to acknowledge Universiti Sains Malaysia (USM) for the University Grant 1001/PTEKIND/8140152. HKF and CSY also thank USM for the Research University Grant 1001/PFIZIK/811160.

References

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Volume 67| Part 7| July 2011| Pages o1719-o1720
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