1-Diphenylmethyl-4-[3-(4-fluorobenzoyl)propyl]piperazine-1,4-diium dichloride monohydrate

In the title compound, C27H31FN2O2+·2Cl−·H2O, the piperazine ring adopts a chair conformation and both N atoms are protonated. The Cl− anions form strong hydrogen bonds to these protons. O/N—H⋯Cl and C—H⋯O hydrogen bonds link the anions, cations and water of hydration into a three-dimensional network.

In the title compound, C 27 H 31 FN 2 O 2+ Á2Cl À ÁH 2 O, the piperazine ring adopts a chair conformation and both N atoms are protonated. The Cl À anions form strong hydrogen bonds to these protons. O/N-HÁ Á ÁCl and C-HÁ Á ÁO hydrogen bonds link the anions, cations and water of hydration into a threedimensional network.
In this article we report the structure of its dihydrochloride monohydrate.
In the title compound ( Fig. 1), the piperazine ring adopts a chair conformation with the piperizine-N atoms protonated.
The Clanions form strong halogen hydrogen bonds to these protons. Two chlorine ions and one hydrone bridge piperazine cations through the O-H···Cl and N-H···Cl halogen hydrogen bonds result in a one-dimensional chain structure. Moreover, these hydrogen bonds, as well as C═O···H hydrogen bonds (Table 1), link the molecular moieties into a two dimensional sheet in the b-c plane. The water of hydration further consolidates the structure via hydrogen bonds of the type O-H···C.
Overall, the individual molecule packs together into a three-dimensional network with a spiral structure motif (Fig. 2).

Experimental
The 1-diphenylmethyl-4-[3-(4-fluorobenzoyl)propyl]piperazine base was synthesized according to a reported procedure (Wang et al., 2003). The title compound was prepared by passing dry hydrochloride gas (100 mg) through a solution of 200 mg base in ethanol (2 ml). The single-crystals of the title compound suitable for X-ray analysis were obtained by vapor diffusion in a solution of chloroform in which the compound was soluble by benzene acting as anti-solvent.