N,N′-Bis(1,3-thiazol-2-yl)methylenediamine

In the title compound, C7H8N4S2, the dihedral angle between the thiazoline rings is 71.25 (13)°. In the crystal, intermolecular N—H⋯N hydrogen bonds connect the molecules into zigzag chains parallel to the ab plane.

In the title compound, C 7 H 8 N 4 S 2 , the dihedral angle between the thiazoline rings is 71.25 (13) . In the crystal, intermolecular N-HÁ Á ÁN hydrogen bonds connect the molecules into zigzag chains parallel to the ab plane.

Comment
The thiazole ring and its derivatives are of great importance in biological systems due to their vast range of biological activities such as anti-inflammatory, analgesic and antipyretic (Raman et al., 2000;Karimian, 2009), especially against certain breast carcinoma cell lines (Shi et al. 1996).
The asymmetric unit of the title compound ( Fig. 1) Bond lengths are in the normal range of thiazole compounds (Odabaşoğlu & Büyükgüngör, 2006;Zhao, et al. 2006). The crystal structure is stabilized by intermolecular N-H···N hydrogen bonds, which link the molecules into zigzag chains (

Experimental
A mixture of formaldehyde (5 mmol) and 2-aminothiazole (10 mmol) and formic acid (0.88 mmol) was added with stirring at room temperature for 24 hrs.The resulting yellow solid was filtered and washed with cold acetonitrile. Single crystals of the title compound were obtained by recrystallization of the colorless solid from acetonitrile.

Refinement
The hydrogen atoms of the N-H groups were found in difference Fourier map and refined isotropically with a distance    Refinement. Refinement of F 2 against ALL reflections. The weighted R-factor wR and goodness of fit S are based on F 2 , conventional R-factors R are based on F, with F set to zero for negative F 2 . The threshold expression of F 2 > σ(F 2 ) is used only for calculating Rfactors(gt) etc. and is not relevant to the choice of reflections for refinement. R-factors based on F 2 are statistically about twice as large as those based on F, and R-factors based on ALL data will be even larger.