Received 6 December 2011
The dimethoxypbenzene ring in the title compound, C19H21NO5, is gauche to the amide group and anti to the ester group. The chirality was confirmed to be S from two-dimensional NMR spectroscopy. In the crystal, N-HO and C-HO hydrogen bonds and several short-contact interactions (2.07-3.45 Å) create chains parallel to . The phenyl ring is disordered over two orientations in a 0.54 (2):0.46 (2) ratio.
Data collection: APEX2 (Bruker, 2006); cell refinement: SAINT (Bruker, 2006; data reduction: SAINT; program(s) used to solve structure: SHELXS97 (Sheldrick, 2008); program(s) used to refine structure: SHELXL97 (Sheldrick, 2008); molecular graphics: OLEX2 (Dolomanov et al., 2009); software used to prepare material for publication: SHELXL97.
Supplementary data and figures for this paper are available from the IUCr electronic archives (Reference: HG5150 ).
The authors wish to thank Dr Hong Su of the Chemistry Department of the University of Cape Town for her assistance with the crystallographic data collection.
Bruker (2006). APEX2 and SAINT. Bruker AXS Inc., Madison, Wisconsin, USA.
Clegg, W. & Elsegood, M. R. J. (2003). Acta Cryst. E59, o1946-o1948.
Dolomanov, O. V., Bourhis, L. J., Gildea, R. J., Howard, J. A. K. & Puschmann, H. (2009). J. Appl. Cryst. 42, 339-341.
Naicker, T., Arvidsson, P. I., Kruger, H. G., Maguire, G. E. M. & Govender, T. (2011). Eur. J. Org. Chem. 34, 6923-6932.
Sheldrick, G. M. (2008). Acta Cryst. A64, 112-122.
Zalán, Z., Martinek, T. A., Lázár, L., Sillanpää, R. & Fülöp, F. (2006). Tetrahedron, 62, 2883-2891.