Received 19 November 2011
In title molecule, C11H11F3N2O2, the central -N-C(=O)-N- unit is essentially planar [maximum deviation = 0.013 (2) Å] and forms a dihedral angle of 57.33 (9)° with the benzene ring. The morpholine ring is in a chair conformation. In the crystal, molecules are linked into chains along  by N-HO hydrogen bonds.
Data collection: CrysAlis PRO (Agilent, 2011); cell refinement: CrysAlis PRO; data reduction: CrysAlis PRO; program(s) used to solve structure: SHELXS97 (Sheldrick, 2008); program(s) used to refine structure: SHELXL97 (Sheldrick, 2008); molecular graphics: OLEX2 (Dolomanov et al., 2009) and PLATON (Spek, 2009); software used to prepare material for publication: OLEX2.
Supplementary data and figures for this paper are available from the IUCr electronic archives (Reference: LH5385 ).
The authors thank the NSFC(81102324) for financial support and Professor Zhihua Mao (Sichuan University) for the X-ray measurements
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Spek, A. L. (2009). Acta Cryst. D65, 148-155.
Zheng, Q. Z., Cheng, H. K., Zhang, X. M., Liu, K., Jiao, Q. C. & Zhu, H. L. (2010). Eur. J. Med. Chem. 45, 3207-3212.