Acta Cryst. (2012). E68, o167-o168  [ doi:10.1107/S1600536811053207 ]

10-Hydroxy-4,9-dimethyl-13-(morpholin-4-ylmethyl)-3,8,15-trioxatetracyclo[10.3.0.0^2,4.0^7,9]pentadecan-14-one

M. Moumou, A. Benharref, A. Oudahmane, F. Mellouki and M. Berraho

Abstract: The title compound, C₁₉H₂₉NO₆, was synthesized from 9-hydroxyparthenolide (9-hydroxy-4,8-dimethyl-12-methylene-3,14-dioxatricyclo[9.3.0.0^2,4]tetradec-7-en-13-one), which was isolated from the chloroform extract of the aerial parts of Anvillea radiata. The molecule contains a fused five- and ten-membered ring system. The ten-membered ring adopts an approximate chair-chair conformation, while the five-membered ring is in an envelope conformation, with the C atom closest to the hydroxy group forming the flap. In the crystal, weak C-HO hydrogen bonds connect the molecules into layers parallel to (001). An intramolecular O-HN hydrogen bond is also present.

Online 17 December 2011

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