Acta Cryst. (2012). E68, o792-o793  [ doi:10.1107/S1600536812005806 ]

4-[3,5-Bis(2-hydroxyphenyl)-1H-1,2,4-triazol-1-yl]benzoic acid dimethylformamide monosolvate

H.-K. Fun, S. Chantrapromma, A. S. Dayananda, H. S. Yathirajan and S. Thomas

Abstract: In the molecule of deferasirox dimethylformamide solvate, C₂₁H₁₅N₃O₄·C₃H₇NO, the central 1,2,4-triazole ring is tilted with respect to the benzoic acid and one of the 2-hydroxyphenyl units but coplanar with the other 2-hydroxyphenyl group, as indicated by the dihedral angles of 33.69 (9), 72.57 (8) and 5.18 (9)°, respectively. Intramolecular O-HN hydrogen bonds generate an S(6) ring motif. In the crystal, deferasirox molecules are linked by O-HN hydrogen bonds and weak C-HO interactions into chains along the c axis. The dimethylformamide solvent molecules are located between the deferasirox chains and are linked to the deferasirox molecules by O-HO hydrogen bonds and weak C-HO interactions.

Online 24 February 2012

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