2-[(2-Aminophenyl)sulfanyl]-N-(4-methoxyphenyl)acetamide

In the title compound, C15H16N2O2S, the dihedral angle between the 4-methoxyaniline and 2-aminobenzenethiole fragments is 35.60 (9)°. A short intramolecular N—H⋯S contact leads to an S(5) ring. In the crystal, molecules are consolidated in the form of polymeric chains along [010] as a result of N—H⋯O hydrogen bonds, which generate R 3 2(18) and R 4 3(22) loops. The polymeric chains are interlinked through C—H⋯O interaction and complete R 2 2(8) ring motifs.

In the title compound, C 15 H 16 N 2 O 2 S, the dihedral angle between the 4-methoxyaniline and 2-aminobenzenethiole fragments is 35.60 (9) . A short intramolecular N-HÁ Á ÁS contact leads to an S(5) ring. In the crystal, molecules are consolidated in the form of polymeric chains along [010] as a result of N-HÁ Á ÁO hydrogen bonds, which generate R 3 2 (18) and R 4 3 (22) loops. The polymeric chains are interlinked through C-HÁ Á ÁO interaction and complete R 2 2 (8) ring motifs.
the concept that amide moiety is an important part of different drugs.
The crystal structure of N-(4-methoxyphenyl)acetamide (Haisa et al., 1980) has been published which is related to the title compound (I, Fig. 1).

Refinement
The H-atoms were positioned geometrically (N-H = 0.86, C-H = 0.93-0.97 Å) and were included in the refinement in the riding model approximation, with U iso (H) = xU eq (C, N), where x = 1.5 for CH 3 and x = 1.2 for other H-atoms.

Figure 2
The partial packing, which shows that molecules form polymeric chains with various ring motifs. The H-atoms not involved in H-bondings are omitted for clarity. where P = (F o 2 + 2F c 2 )/3 (Δ/σ) max < 0.001 Δρ max = 0.18 e Å −3 Δρ min = −0.20 e Å −3 Special details Geometry. Bond distances, angles etc. have been calculated using the rounded fractional coordinates. All su's are estimated from the variances of the (full) variance-covariance matrix. The cell e.s.d.'s are taken into account in the estimation of distances, angles and torsion angles Refinement. Refinement of F 2 against ALL reflections. The weighted R-factor wR and goodness of fit S are based on F 2 , conventional R-factors R are based on F, with F set to zero for negative F 2 . The threshold expression of F 2 > σ(F 2 ) is used only for calculating R-factors(gt) etc. and is not relevant to the choice of reflections for refinement. R-factors based on F 2 are statistically about twice as large as those based on F, and R-factors based on ALL data will be even larger.