Received 5 March 2012
In the title molecule, C21H19FN4O, the triazole ring forms dihedral angles of 67.0 (1) and 59.6 (1)° with the phenyl and fluoro-substituted benzene rings, respectively. The dihedral angle between the phenyl ring and the fluoro-substituted benzene ring is 79.1 (1)°. The pyrrolidine ring is in a half-chair conformation. In the crystal, weak C-HO and C-HN hydrogen bonds connect molecules into layers parallel to (001).
For clinical uses of triazole compounds, see: Wang & Zhou (2011); Zhou & Wang (2012); Chang et al. (2011). For the synthesis, see: Solankee et al. (2010). For related structures, see: Wang et al. (2009); Yan et al. (2009).
Data collection: SMART (Bruker, 1997); cell refinement: SAINT (Bruker, 1997); data reduction: SAINT; program(s) used to solve structure: SHELXS97 (Sheldrick, 2008); program(s) used to refine structure: SHELXL97 (Sheldrick, 2008); molecular graphics: PLATON (Spek, 2009); software used to prepare material for publication: SHELXTL (Sheldrick, 2008).
Supplementary data and figures for this paper are available from the IUCr electronic archives (Reference: LH5432 ).
This work was partially supported by the Natural Science Foundation of China (21172181) and the Research Funds for the Central Universities, the key program of the Natural Science Foundation of Chongqing (CSTC2012jjB10026), the Specialized Research Fund for the Doctoral Program of Higher Education of China (SRFDP 20110182110007) and the Research Funds for the Central Universities (XDJK2011D007, XDJK2012B026).
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