1,2-Diphenyl-2-[(1-phenylethyl)amino]ethanol

In the molecule of the title compound, C22H23NO, there are two chiral atoms (R* for the C atom attached to the OH group and S* for the C atom attached to the phenyl ring). In the crystal, neighbouring molecules are connected into a chain along the b axis by N—H⋯O hydrogen bonds.

In the molecule of the title compound, C 22 H 23 NO, there are two chiral atoms (R* for the C atom attached to the OH group and S* for the C atom attached to the phenyl ring). In the crystal, neighbouring molecules are connected into a chain along the b axis by N-HÁ Á ÁO hydrogen bonds.

Experimental
Benzil (0.75 g, 3.6 mmol) was added to a stirred ethanol solution of R-phenylethylamine (0.87 g, 3.96 mmol) in a roundbottomed flask under a nitrogen atmosphere and heated until ethanol refluxed. This reaction took about 31 h. In the ice bath environment, sodium borohydride (0.27 g, 7.92 mmol) was added to the mixture in batches. Then drained ethanol, white solid was obtained. The crude product was extracted with dichloromethane three times. The organic phase was dried over anhydrous magnesium sulfate and then evaporated. The pure product was obtained after recrystallized with petroleum ether. Single crystal of the title compound suitable for X-ray diffraction were obtained by slow evaporation of petroleum ether solution of the title compound.

Refinement
All H atoms attached to C N O atoms were fixed geometrically and treated as riding with C-H = 0.93 -0.98 Å, N-H = 0.90 Å, O-H = 0.820 Å with U iso (H) = 1.5 U eq (methyl) and U iso (H) = 1.2 U eq (C) for all other H atoms.In the absence of significant anomalous scattering, Friedel pairs were merged and the absolute structure was assigned arbitrarily.  The molecular structure of the compound. Displacement ellipsoids are drawn at the 50% probability level.

Figure 2
The one-dimensional chain, linked by N-H···O hydrogen bonds.  Refinement. Refinement of F 2 against ALL reflections. The weighted R-factor wR and goodness of fit S are based on F 2 , conventional R-factors R are based on F, with F set to zero for negative F 2 . The threshold expression of F 2 > σ(F 2 ) is used only for calculating R-factors(gt) etc. and is not relevant to the choice of reflections for refinement. R-factors based on F 2 are statistically about twice as large as those based on F, and R-factors based on ALL data will be even larger.

Fractional atomic coordinates and isotropic or equivalent isotropic displacement parameters (Å 2 )
x y z U iso */U eq N1 0.1361 (