Received 8 October 2012
aDepartment of Studies in Physics, Manasagangotri, University of Mysore, Mysore 570 006, India,bPG Department of Studies in Chemistry, JSS College of Arts, Commerce and Science, Ooty Road, Mysore 570 025, India, and cX-ray Crystallography Laboratory, Post-Graduate Department of Physics & Electronics, University of Jammu, Jammu Tawi 180 006, India
Correspondence e-mail: firstname.lastname@example.org
The title compound, C22H23BrN4O3S2, crystallizes with two molecules, A and B, in the asymmetric unit. In one of these, the methoxy group is disordered over two sets of sites in a 0.565 (9):0.435 (9) ratio. The benzene rings bridged by the sulfonamide group are tilted relative to each other by 37.4 (1) and 56.1 (1)° in molecules A and B, respectively, while the dihedral angles between the sulfur-bridged pyrimidine and benzene rings are 72.4 (1) and 70.2 (1)° for A and B, respectively. The piperidine ring adopts a chair conformation in both molecules. In the crystal, inversion dimers linked by pairs of N-HN hydrogen bonds occur for both A and B; the dimers are linked into  chains by C-HO hydrogen bonds. The crystal structure also features inversion-generated aromatic - stacking interactions between the pyrimidine rings for both molecules [centroid-centroid distances = 3.412 (2) (molecule A) and 3.396 (2) Å (molecule B)].
For the biological activity of sulfonamide compounds, see: Lee et al. (2002); Laurence (2009). For related structures, see: Rodrigues et al. (2011); Akkurt et al. (2011); Kant et al. (2012); Kumar et al. (2012).
Data collection: CrysAlis PRO (Oxford Diffraction, 2010); cell refinement: CrysAlis PRO; data reduction: CrysAlis PRO; program(s) used to solve structure: SHELXS97 (Sheldrick, 2008); program(s) used to refine structure: SHELXL97 (Sheldrick, 2008); molecular graphics: ORTEP-3 (Farrugia, 1997); software used to prepare material for publication: PLATON (Spek, 2009).
Supplementary data and figures for this paper are available from the IUCr electronic archives (Reference: HB6971 ).
MK acknowledges the help of Bahubali College of Engineering, Shravanabelagola, for his research work. RK acknowledges the Department of Science & Technology for the single-crystal X-ray diffractometer sanctioned as a National Facility under project No. SR/S2/CMP-47/2003.
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