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Acta Cryst. (2012). E68, o3136
[ doi:10.1107/S1600536812042432 ]

7-[(3-Chloro-6-methyl-6,11-dihydrodibenzo[c,f][1,2]thiazepin-11-yl)amino]heptanoic acid S,S-dioxide hydrochloride

A. Mishnev, A. Zvirgzdins, A. Actins and M. Delina

Abstract: In the title compound, C21H26ClN2O4S.Cl, also known as tianeptine hydrochloride, the seven-membered ring adopts a boat conformation. The dihedral angle between the mean planes of the benzene rings is 44.44 (7)°. There is an intramolecular hydrogen bond formed via S= O...H-N. In the crystal, molecules are connected via pairs of N-H.·O, N-H...Cl and O-H...Cl hydrogen bonds, forming inversion dimers, which are consolidated by C-H...O interactions. The dimers are linked by C-H...O and C-H...Cl interactions, forming a two-dimensional network lying parallel to (011).


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