Received 30 September 2012
aDepartment of Studies in Physics, Manasagangotri, University of Mysore, Mysore 570 006, India,bDepartment of Chemistry, Yuvaraja's College, University of Mysore, Mysore 570 005, India,cDepartment of Physics, St Philomena's College, Mysore, India, and dSER-CAT, APS, Argonne National Laboratory, Argonne, IL-60439, USA
Correspondence e-mail: email@example.com
In the title compound C11H9NO2, the phenyl and isoxazole rings are almost coplanar, making a dihedral angle of 1.14 (9)°. This planarity is also assisted by an intramolecular C-HO hydrogen bond between the phenyl ring and the carbonyl O atom. In the crystal, weak C-HO interactions generate a layered structure parallel to the ac plane.
For the biological and therapeutic importance of isoxazoles, see: Kang et al. (2000); Conti et al. (1998); Changtam et al. (2010); Kwon et al., (1995); Abbiati et al. (2003). For bond-length and angle data in a related structure, see: Wolf et al. (1995).
Data collection: APEX2 (Bruker, 2009); cell refinement: SAINT (Bruker, 2009); data reduction: SAINT; program(s) used to solve structure: SHELXS97 (Sheldrick, 2008); program(s) used to refine structure: SHELXL97 (Sheldrick, 2008); molecular graphics: PLATON (Spek, 2009); software used to prepare material for publication: SHELXL97.
Supplementary data and figures for this paper are available from the IUCr electronic archives (Reference: SJ5268 ).
MM would like to thank the University of Mysore for the award of project DV3/136/2007-2008/24.09.09.
Abbiati, G., Beccalli, E. M., Broggini, G. & Zoni, C. (2003). Tetrahedron, 59, 9887-9893.
Bruker (2009). APEX2 and SAINT. Bruker AXS Inc., Madison, Wisconsin, USA.
Changtam, C., Hongmanee, P. & Suksamrarn, A. (2010). Eur. J. Med. Chem. 45, 4446-4457.
Conti, P., Dallanoce, C., Amici, M. D., Micheli, C. D. & Klotz, K. N. (1998). Bioorg. Med. Chem. 6, 401-408.
Kang, Y. Y., Shin, K. L., Yoo, K. H., Seo, K. J., Hong, C. Y., Lee, C. S., Park, S. Y., Kim, D. J. & Park, S. W. (2000). Bioorg. Med. Chem. Lett. 10, 95-99.
Kwon, T., Heimann, A. S., Oriaku, E. T., Yoon, K. & Lee, H. J. (1995). J. Med. Chem. 38, 1048-1051.
Sheldrick, G. M. (2008). Acta Cryst. A64, 112-122.
Spek, A. L. (2009). Acta Cryst. D65, 148-155.
Wolf, R., Wong, M. W., Kennard, C. H. L. & Wentrup, C. (1995). J. Am. Chem. Soc. 117, 6789-6790.