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Acta Cryst. (2012). E68, o3358-o3359
[ doi:10.1107/S1600536812046405 ]

Morphine hydrochloride anhydrate

T. Gelbrich, D. E. Braun and U. J. Griesser

Abstract: In the title molecular salt [systematic name: (5[alpha],6[alpha])-7,8-didehydro-4,5-epoxy-17-methylmorphinan-3,6-diol hydrochloride], C17H20NO3+·Cl-, the conformation of the morphinium ion is in agreement with the characteristics of the previously reported morphine forms [for example, Gylbert (1973). Acta Cryst. B29, 1630-1635]. In the crystal, the cations and chloride anions are linked into a helical chain propagating parallel to the b-axis direction by N-H...Cl and O-H...Cl hydrogen bonds. The title salt and the morphine monohydrate [Bye (1976) Acta Chem. Scand. 30, 549-554] display very similar one-dimensional packing modes of their morphine components.

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