Received 14 October 2012
aDepartment of Studies and Research in Chemistry, Tumkur University, Tumkur, Karnataka 572 103, India,bDepartment of Studies and Research in Chemistry, U.C.S, Tumkur University, Tumkur, Karnataka 572 103, India, and cDepartment of Studies and Research in Physics, U.C.S, Tumkur University, Tumkur, Karnataka 572 103, India
Correspondence e-mail: email@example.com
In the title compound, C10H20N4O3, the piperazine ring adopts a chair conformation. The molecule adopts an E conformation across the C=N double bond, with the -OH group and the piperazine ring trans to one another. Further, the H atom of the hydroxy group is directed away from the NH2 group. An intramolecular N-HO contact occurs involving the NH2 group and the oxime O atom. In the crystal, molecules are linked via strong N-HO and O-HN hydrogen bonds with alternating R22(6) and C(9) motifs into tetrameric units forming R44(28) motifs.
For the synthesis, characterization and biological activity of piperazine and its derivatives, see: Gan et al. (2009a,b); Willems & Ilzerman (2010). For a related structure, see: Gowda et al. (2009). For hydrogen-bond motifs, see: Bernstein et al. (1995); Etter (1990).
Data collection: SMART (Bruker, 2004); cell refinement: SAINT-Plus (Bruker, 2004); data reduction: SAINT-Plus and XPREP (Bruker, 2004); program(s) used to solve structure: SHELXS97 (Sheldrick, 2008); program(s) used to refine structure: SHELXL97 (Sheldrick, 2008); molecular graphics: ORTEP-3 (Farrugia, 2012); software used to prepare material for publication: SHELXL97.
Supplementary data and figures for this paper are available from the IUCr electronic archives (Reference: ZJ2096 ).
The authors thank Dr S. C. Sharma, Vice Chancellor, Tumkur University, Tumkur for his constant encouragement. and G. B. Sadananda, Department of Studies and Research in Physics, U. C. S. Tumkur University, Tumkur, for his help and valuable suggestions. BSPM thanks Dr H. C. Devarajegowda, Department of Physics Yuvarajas College (constituent), University of Mysore, for his guidance.
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