Received 25 November 2012
aDepartment of Physics, The Madura College, Madurai 625 011, India,bDepartment of Organic Chemistry, School of Chemistry, Madurai Kamaraj University, Madurai 625 021, India, and cDepartment of Food Science and Technology, University of Ruhuna, Mapalana, Kamburupitiya 81100, Sri Lanka
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In the title compound, C25H25ClO2, the C ring adopts a chair conformation, while the B ring approximates a half-chair conformation. The five-membered ring D has a twist conformation on the C-C bond fused with the C ring. Aromatic rings A and E are not coplanar, as evidenced by the dihedral angle of 7.51 (1)°. In the crystal, O-HO hydrogen bonds form a double chain along the ab plane interconnected by C-HO interactions.
For applications of steroids as radiodiagnostic compounds and drug delivery systems, see: Katzenellenbogen (1995); Silva et al. (2001); Wang et al. (2003). For related compounds, see: Cooper et al. (1969); Cody et al. (1971); Rajnikant et al. (2006); Gunasekaran et al. (2009). For conformational analysis of ring systems, see: Cremer & Pople (1975); Duax et al. (1976).
Data collection: APEX2 (Bruker, 2004); cell refinement: SAINT (Bruker, 2004); data reduction: SAINT; program(s) used to solve structure: SHELXS97 (Sheldrick, 2008); program(s) used to refine structure: SHELXL97 (Sheldrick, 2008); molecular graphics: PLATON (Spek, 2009); software used to prepare material for publication: SHELXL97.
Supplementary data and figures for this paper are available from the IUCr electronic archives (Reference: BH2467 ).
JS thanks the UGC for the FIST support. JS and HT thank the management of Madura College for their encouragement and support. RRK thanks the DST, New Delhi for funds under the fast-track scheme (No. SR/FT/CS-073/2009)
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