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Acta Cryst. (2013). E69, o217
[ doi:10.1107/S1600536813000305 ]


A. Rivera, D. Quiroga, J. Ríos-Motta, M. Kuceraková and M. Dusek

Abstract: In the crystal structure of the title compound, C21H24F2N2O2, there are two intramolecular O-H...N hydrogen bonds involving the N atoms of the imidazolidine ring and the hydroxy groups. The crystal studied was a meso compound obtained by the reaction of the aminal (2S,7R,11S,16R)-1,8,10,17-tetraazapentacyclo[,17.02,7.011,16]cosane with 4-fluorophenol. The imidazolidine ring has a twisted conformation with a CH-CH-N-CH2 torsion angle of 44.99 (14)° and, surprisingly, the lone pairs of the N atoms are disposed in a syn isomerism, making the title compound an exception to the typical `rabbit-ear effect' in 1,2-diamines. In the crystal, molecules are linked via C-H...F hydrogen bonds, forming chains along the c-axis direction. These chains are linked via another C-H...F hydrogen bond, forming a three-dimensional network.

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