2-[5-(2-Fluorophenyl)-3-isobutyl-1H-pyrazol-1-yl]benzoic acid

In the title compound, C20H19FN2O2, the dihedral angle between the aromatic rings is 62.1 (1)°, and those between the pyrazole ring and the fluorobenzene and benzoic acid rings are 52.1 (1) and 53.1 (1)°, respectively. In the crystal, molecules are linked into [010] C(7) chains by O—H⋯N hydrogen bonds.

In the title compound, C 20 H 19 FN 2 O 2 , the dihedral angle between the aromatic rings is 62.1 (1) , and those between the pyrazole ring and the fluorobenzene and benzoic acid rings are 52.1 (1) and 53.1 (1) , respectively. In the crystal, molecules are linked into [010] C(7) chains by O-HÁ Á ÁN hydrogen bonds.

Palakshamurthy Comment
The pyrazole nucleus is an important structure in numerous natural and synthetic compounds and in medicinal chemistry (e.g. Ramaiah et al., 1999). As part of our studies in this area, the title compound was synthesized and its crystal structure determined.
In the title compound, C 20 H 19 FN 2 O 2 , the dihedral angle between the aromatic rings is 62.1 (1)°, and those between the pyrazole ring and the aromatic ring containing fluorine atom and the pyrazole ring and the aromatic ring containing carboxylic group are 52.1 (1)° and 53.1 (1)°, respectively. In the crystal structure, the molecules are linked into C(7) chains through O-H···N H-bonds.
Colourless prisms were obtained by slow evaporation of the solution of the compound in a mixture of dichloromethane and methanol (9:1).

Refinement
The H atoms were positioned with idealized geometry using a riding model with C-H = 0.93-0.97 Å. All C-H atoms were refined with isotropic displacement parameters (set to 1.2-1.5 times of the U eq of the parent atom) and O-H atoms were refined freely  Molecular structure of the title compound, showing displacement ellipsoids drawn at the 50% probability level.