Received 20 November 2012
In the title compound, C13H18N2O4, the dihedral angle between the benzene and pyrrolidine (all atoms) rings is 70.6 (1)°. The pyrrolidine ring adopts a half-chair conformation. In the crystal, molecules form chains along the c-axis direction linked by O-HN hydrogen bonds, which are then connected by C-HO interactions, forming a sheet parallel to the bc plane.
For information on the pyrrolidine ring in biologically active natural compounds, see: Gu et al. (2004). For the use of pyrrolidine-containing molecules in the treatment of diseases, see, for example: Horri et al. (1986) for diabetes and Karpas et al. (1988) for viral infections. For bond lengths in a related structure, see: Jayabharathi et al. (2009).
Data collection: APEX2 (Bruker, 2004); cell refinement: SAINT (Bruker, 2004); data reduction: SAINT and XPREP (Bruker, 2004); program(s) used to solve structure: SHELXS97 (Sheldrick, 2008); program(s) used to refine structure: SHELXL97 (Sheldrick, 2008); molecular graphics: ORTEP-3 for Windows (Farrugia, 2012); software used to prepare material for publication: SHELXL97 and PLATON (Spek, 2009).
Supplementary data and figures for this paper are available from the IUCr electronic archives (Reference: NK2193 ).
The authors thank Professor D. Velmurugan, Centre for Advanced Study in Crystallography and Biophysics, University of Madras, for providing data collection and computer facilities.
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