Acta Crystallographica Section E

Structure Reports Online

Volume 69, Part 4 (April 2013)

organic compounds

Acta Cryst. (2013). E69, o584    [ doi:10.1107/S1600536813007460 ]


G. Shan, Z. Li, L. Hu, J. Jiang and Z. Liu

Abstract: In the title compound, C20H19N3O4S, a novel tubulin ligand active against human cancer, the dihedral angle between the pyridine ring and the carbazole ring system is 42.87 (10)°. In the crystal, the mol­ecules are held together by N-H...O and C-H...O hydrogen bonds into layers, which are assembled into a three-dimensional network via [pi]-[pi] stacking inter­actions between inversion-related pyridine rings, with centroid-centroid distances of 3.5101 (12) Å.

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