Received 27 January 2013
In the pregnene fragment of the title compound, C27H38ClN, the three six-membered rings exhibit chair conformations and the five-membered ring has a distorted envelope form with the fused C atom not bearing a methyl group as the flap atom. The amino group is involved in the formation of an intramolecular N-HCl hydrogen bond. The crystal packing exhibits no short intermolecular contacts.
For applications of pregnene-type steroidal alkaloid derivatives, see: Hua et al. (2005); Hunter & Priest (2006). For the crystal structure of the related compound (Z)-3-(1,3-dioxoisoindolin-2-yl)-17 (20)-pregnene, see: Qi et al. (2011).
Data collection: CrystalClear (Rigaku/MSC, 2005); cell refinement: CrystalClear; data reduction: CrystalClear; program(s) used to solve structure: SHELXS97 (Sheldrick, 2008); program(s) used to refine structure: SHELXL97 (Sheldrick, 2008); molecular graphics: SHELXTL (Sheldrick, 2008); software used to prepare material for publication: CrystalStructure (Rigaku/MSC, 2005).
Supplementary data and figures for this paper are available from the IUCr electronic archives (Reference: CV5384 ).
This project was supported by the Science and Technology Department of Liaoning Province Science Foundation (grant No. 2010226003), Graduate Education Innovation Program 2010.
Flack, H. D. (1983). Acta Cryst. A39, 876-881.
Hua, Z. H., Carcache, D. A., Tian, Y., Li, Y.-M. & Danishiefsky, S. J. (2005). J. Org. Chem. 702, 9849-9856.
Hunter, A. C. & Priest, S.-M. (2006). Steroids, 71, 30-33.
Qi, Y., Qin, N. & Duan, H.-Q. (2011). Acta Cryst. E67, o2065.
Rigaku/MSC (2005). CrystalClear and CrystalStructure. Rigaku/MSC, The Woodlands, Texas, USA.
Sheldrick, G. M. (2008). Acta Cryst. A64, 112-122.