Received 12 March 2013
aInstitute of Radioisotope Research, St. Marianna University Graduate School of Medicine, 2-16-1 Sugao, Miyamae-ku, Kawasaki, Kanagawa 216-8511, Japan,bDepartment of Molecular and Behavioral Neuroscience, St. Marianna University Graduate School of Medicine, 2-16-1 Sugao, Miyamae-ku, Kawasaki, Kanagawa 216-8511, Japan, and cSchool of Science, Kitasato University, 1-15-1 Kitasato, Minami-ku, Sagamihara, Kanagawa 252-0373, Japan
Correspondence e-mail: firstname.lastname@example.org
In the title compound, C10H19N3O4, the N- and C-termini are protonated and ionized, respectively, and the molecule forms a zwitterion. The main chain is in a folded form. In the crystal, the N-terminal -NH3+ group hydrogen bonds to three C-terminal -COO groups and one carbonyl O atom, forming a three-dimensional network. In addition, an N-HO hydrogen bond between the amide groups of the middle glycine residue and a C-HO interaction continue along the a-axis direction. The side chains of the leucyl residues form a hydrophobic region along the a axis.
Data collection: CrystalClear (Rigaku, 2006); cell refinement: CrystalClear; data reduction: CrystalClear; program(s) used to solve structure: SHELXS97 (Sheldrick, 2008); program(s) used to refine structure: SHELXL97 (Sheldrick, 2008); molecular graphics: Mercury (Macrae et al., 2006); software used to prepare material for publication: SHELXL97 (Sheldrick, 2008) and Yadokari-XG 2009 (Kabuto et al., 2009).
Supplementary data and figures for this paper are available from the IUCr electronic archives (Reference: IS5257 ).
This work was partially supported by the JSPS KAKENHI (grant Nos. 24659548 and 23540478) and MEXT KAKENHI (grant No. 23108003).
Goswami, K. N., Yadava, V. S. & Padmanabhan, V. M. (1977). Acta Cryst. B33, 1280-1283.
Kabuto, C., Akine, S., Nemoto, T. & Kwon, E. (2009). J. Cryst. Soc. Jpn, 51, 218-224.
Kiyotani, T. & Sugawara, Y. (2012). Acta Cryst. C68, o498-o501.
Macrae, C. F., Edgington, P. R., McCabe, P., Pidcock, E., Shields, G. P., Taylor, R., Towler, M. & van de Streek, J. (2006). J. Appl. Cryst. 39, 453-457.
Rigaku (2006). CrystalClear. Rigaku Corporation, Tokyo, Japan.
Sheldrick, G. M. (2008). Acta Cryst. A64, 112-122.
Srikrishnan, T. & Parthasarathy, R. (1987). Int. J. Pept. Protein Res. 30, 557-563.