Received 30 March 2013
aDepartment of Chemistry, School of Preclinical Medicine, Shanxi Medical University, 56 Xinjian South Road, 030001 Tai Yuan, People's Republic of China,bAffiliated Hospital of Xi'an Medical College, 48 Fenggao West Road, 710077 Xi-An, People's Republic of China, and cDepartment of Chemistry, School of Pharmacy, Fourth Military Medical University, Changle West Road 17, 710032 Xi-An, People's Republic of China
Correspondence e-mail: email@example.com
In the title compound, C13H13NO3, the isoxazole ring is approximately coplanar with the phenyl ring, the dihedral angle between their planes being 7.37 (19)°. In the crystal, centrosymmetrically related molecules are linked into dimers by pairs of C-HO hydrogen bonds, generating a ring of graph-set motif R22(10).
For the biological activity of isoxazole derivatives, see: Angibaud et al. (2003). For the structure of a related compound, see: Yao & Deng (2008). For the synthesis of 3-phenylisoxazole-5-carboxylic acid, see: Liu et al. (2006).
Data collection: APEX2 (Bruker, 2008); cell refinement: SAINT (Bruker, 2008); data reduction: SAINT; program(s) used to solve structure: SHELXS97 (Sheldrick, 2008); program(s) used to refine structure: SHELXL97 (Sheldrick, 2008); molecular graphics: SHELXTL (Sheldrick, 2008); software used to prepare material for publication: publCIF (Westrip, 2010).
Supplementary data and figures for this paper are available from the IUCr electronic archives (Reference: RZ5055 ).
This work was supported financially by the National Natural Science Foundation of China (21172262).
Angibaud, P., Bourdrez, X., Devine, A., End, D. W., Freyne, E., Ligny, Y., Muller, P., Mannens, G., Pilatte, I., Poncelet, V., Skrzat, S., Smets, G., Van Dun, J., Van Remoortere, P., Venet, M. & Wouters, W. (2003). Bioorg. Med. Chem. Lett. 13, 1543-1548.
Bruker (2008). APEX2, SAINT and SADABS. Bruker AXS Inc., Madison, Wisconsin, USA.
Liu, L.-J., Yong, J.-P., Dai, X.-J., Jia, J., Wang, X.-Z. & Wang, J.-W. (2006). Chem. J. Chin. Univ. 27, 1669-1672.
Sheldrick, G. M. (2008). Acta Cryst. A64, 112-122.
Westrip, S. P. (2010). J. Appl. Cryst. 43, 920-925.
Yao, Z. & Deng, J.-C. (2008). Acta Cryst. E64, o131.