Received 23 May 2013
In the title compound, C29H27N3O5, the hydropyran ring adopts an envelope conformation with the methine C atom bearing the para-methoxybenzene ring as the flap. The central pyrrolidine ring has a twist conformation on the N-C bond involving the spiro C atom. The piperidine ring adopts a chair conformation. An intramolecular C-HO contact closes an S(7) ring. In the crystal, inversion dimers linked by C-HO interactions generate R22(18) loops and N-HO hydrogen bonds connect the dimers into  chains.
Data collection: APEX2 (Bruker, 2008); cell refinement: SAINT (Bruker, 2008); data reduction: SAINT; program(s) used to solve structure: SHELXS97 (Sheldrick, 2008); program(s) used to refine structure: SHELXL97 (Sheldrick, 2008); molecular graphics: ORTEP-3 for Windows (Farrugia, 2012); software used to prepare material for publication: SHELXL97 and PLATON (Spek, 2009).
Supplementary data and figures for this paper are available from the IUCr electronic archives (Reference: HB7087 ).
The authors thank the TBI X-ray facility, CAS in Crystallography and Biophysics, University of Madras, India, for the data collection. SK,TS and DV thank the UGC (SAP-CAS) for the departmental facilties. SK also thanks DST PURSE for a Junior Research Fellowship and TS also thanks DST Inspire for a fellowship.
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Devi, S. K., Srinivasan, T., Rao, J. N. S., Raghunathan, R. & Velmurugan, D. (2013). Acta Cryst. E69, o993.
Farrugia, L. J. (2012). J. Appl. Cryst. 45, 849-854.
Sheldrick, G. M. (2008). Acta Cryst. A64, 112-122.
Spek, A. L. (2009). Acta Cryst. D65, 148-155.