Received 28 May 2013
aDepartment of Chemistry, College of Science, King Saud University, PO Box 2455, Riyadh 11451, Saudi Arabia,bDepartment of Chemistry, Faculty of Science, Alexandria University, PO Box 426, Ibrahimia 21321 Alexandria, Egypt, and cH.E.J. Research Institute of Chemistry, International Center for Chemical and Biological Sciences, University of Karachi, Karachi 75270, Pakistan
Correspondence e-mail: firstname.lastname@example.org
In the title compound, C16H17NO3S, a thiophene derivative with amino phenyl, acetyl, methyl and ethyl carboxyl susbtituents attached to a central thiophene ring, the phenyl and thiophene rings form a dihedral angle of 36.92 (9) Å. The molecular conformation is stabilized by an intramolecular N-HO hydrogen bond, which forms an S(6) ring motif.
For the biological activity of thiophene derivatives, see: Mishra et al. (2011); Mabkhot et al. (2013b). For the synthesis of fused heterocyclic compounds, see: Sommen et al. (2003). For crystal data for related thiophene compounds, see: Mabkhot et al. (2013a,b); Buehrdel et al. (2007).
Data collection: SMART (Bruker, 2000); cell refinement: SAINT (Bruker, 2000); data reduction: SAINT; program(s) used to solve structure: SHELXS97 (Sheldrick, 2008); program(s) used to refine structure: SHELXL97 (Sheldrick, 2008); molecular graphics: SHELXTL; software used to prepare material for publication: SHELXTL, PARST (Nardelli, 1995) and PLATON (Spek, 2009).
Supplementary data and figures for this paper are available from the IUCr electronic archives (Reference: RZ5071 ).
The authors are thankful to King Saud University, Deanship of Scientific Research, College of Science Research Center, for financial support of this project.
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