Received 6 June 2013
In the title compound, C14H15BrN2O2S, synthesized by the reaction of the corresponding phenacyl thiocyanate with morpholine, the dihedral angle between the 1,3-thiazole ring and the phenolic substituent ring is 23.46 (10)° as a result of the steric influence of the ortho-methyl group on the thiazole ring. A strong intramolecular phenolic O-HN hydrogen bond is present in the molecule. In the crystal, a weak C-HOphenol hydrogen bond gives rise to chains lying parallel to [20-1]. A short intermolecular BrOmorpholine interaction is also present [3.1338 (19) Å].
For details of the synthesis, see: Seliger et al. (1997). For a recent review on thiazoles, see: Zagade & Senthilkumar (2011). For the pharmacological activity and applications of thiazole derivatives, see: Ghaemmaghami et al. (2010); Coco & Onnis (1993); Gewald et al. (1994); Tanaka et al. (1994); Zimmermann et al. (1990).
Data collection: X-AREA (Stoe & Cie, 2002); cell refinement: X-AREA; data reduction: X-RED (Stoe & Cie, 2002); program(s) used to solve structure: SHELXS97 (Sheldrick, 2008); program(s) used to refine structure: SHELXL97 (Sheldrick, 2008); molecular graphics: XP in SHELXTL (Sheldrick, 2008); software used to prepare material for publication: SHELXL97.
Supplementary data and figures for this paper are available from the IUCr electronic archives (Reference: ZS2266 ).
Part of this work was supported by a grant of the Romanian National Authority for Scientific Research, CNDI-UEFISCDI, project No. 51/2012.
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