3-(3-Methylphenyl)-5-(quinolin-8-ylmethoxy)-1,2,4-oxadiazole monohydrate

In the title compound, C19H15N3O2·H2O, the oxadiazole ring and the quinoline unit are almost coplanar, making a dihedral angle of 7.66 (8)°. The dihedral angle between the benzene ring and the quinoline system is 25.95 (8)° while that between the benzene and the oxadiazole rings is 18.88 (9)°. The water molecule is hydrogen bonded to an oxadiazole N atom and to the quinoline N atom. In the crystal, these units are linked via C—H⋯O hydrogen bonds, forming two-dimensional networks lying parallel to the ab plane.

In the title compound, C 19 H 15 N 3 O 2 ÁH 2 O, the oxadiazole ring and the quinoline unit are almost coplanar, making a dihedral angle of 7.66 (8) . The dihedral angle between the benzene ring and the quinoline system is 25.95 (8) while that between the benzene and the oxadiazole rings is 18.88 (9) . The water molecule is hydrogen bonded to an oxadiazole N atom and to the quinoline N atom. In the crystal, these units are linked via C-HÁ Á ÁO hydrogen bonds, forming two-dimensional networks lying parallel to the ab plane.
Supplementary data and figures for this paper are available from the IUCr electronic archives (Reference: IM2428).
Crystals suitable for X-ray analysis were obtained by slow evaporation of an ethyl acetate solution.

Refinement
H atoms were positioned geometrically, with C-H = 0.93, 0.97 and 0.96 Å for aromatic, methylene and methyl H, respectively, and constrained to ride on their parent atoms, with U iso (H) = xU eq (C,N), where x = 1.5 for methyl H and x = 1.2 for all other H atoms. Hydrogen atoms of the solvent water molecule have been determined from Fourier maps and refined freely.  Molecular structure of the title molecule with displacement ellipsoids drawn at the 50% probability level.

Figure 2
Packing diagram of the title compound. Hydrogen bonds are shown as dashed lines.  (7) Special details Geometry. All esds (except the esd in the dihedral angle between two l.s. planes) are estimated using the full covariance matrix. The cell esds are taken into account individually in the estimation of esds in distances, angles and torsion angles; correlations between esds in cell parameters are only used when they are defined by crystal symmetry. An approximate (isotropic) treatment of cell esds is used for estimating esds involving l.s. planes. Refinement. Refinement of F 2 against ALL reflections. The weighted R-factor wR and goodness of fit S are based on F 2 , conventional R-factors R are based on F, with F set to zero for negative F 2 . The threshold expression of F 2 > 2sigma(F 2 ) is used only for calculating R-factors(gt) etc. and is not relevant to the choice of reflections for refinement. R-factors based on F 2 are statistically about twice as large as those based on F, and R-factors based on ALL data will be even larger.