Received 19 July 2013
aCollege of Pharmacy, Nanjing University of Chinese Medicine, Nanjing 210023, People's Republic of China,bDepartment of Applied Chemistry, Nanjing College of Chemical Technology, Nanjing 210048, People's Republic of China,cMolecular Biology Laboratory of SATCM, First Medicine College, Nanjing University of Chinese Medicine, Nanjing 210023, People's Republic of China, and dScience and Technology Department, Nanjing University of Chinese Medicine, Nanjing 210023, People's Republic of China
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In the title compound, C14H12N2O3, the pyridine ring is twisted with respect to the phenyl ring and the carboxylic acid group at angles of 37.1 (5) and 8.1 (3)°, respectively; the phenyl ring forms a dihedral angle of 41.4 (1)° with the mean plane of the C-NH-C=O fragment. An intramolecular O-HO hydrogen bond occurs between the carboxylic acid and carbonyl groups. In the crystal, N-HO hydrogen bonds link molecules into a supramolecular chain running along the a-axis direction.
Data collection: CAD-4 EXPRESS (Enraf-Nonius, 1994); cell refinement: CAD-4 EXPRESS; data reduction: XCAD4 (Harms & Wocadlo,1995); program(s) used to solve structure: SHELXTL (Sheldrick, 2008); program(s) used to refine structure: SHELXTL; molecular graphics: SHELXTL; software used to prepare material for publication: SHELXTL.
Supplementary data and figures for this paper are available from the IUCr electronic archives (Reference: XU5724 ).
The authors thank the Center of Testing and Analysis, Nanjing University, for the data collection.
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Harms, K. & Wocadlo, S. (1995). XCAD4. University of Marburg, Germany.
Koch, C., Görls, H. & Westerhausen, M. (2008). Acta Cryst. E64, o2358.
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Sheldrick, G. M. (2008). Acta Cryst. A64, 112-122.