Received 3 September 2013
The asymmetric unit of the title compound, C19H19NOS, contains two independent molecules (A and B), in both of which the 1,3-thiazepan-4-one ring adopts a chair-type conformation. The dihedral angles between the two phenyl rings are 65.28 (8) and 60.31 (9)° for molecules A and B, respectively. In the crystal, molecules are linked by weak C-HO interactions, resulting in a three-dimensional network.
For amide bond formation using 2,4,6-tripropyl-1,3,5,2,4,6-trioxatriphosphorinane-2,4,6-trioxide (T3P), see: Dunetz et al. (2011). For preparation of various heterocycles using imines and T3P, see: Unsworth et al. (2013). For omapatrilat, see: Graul et al. (1999); Robl et al. (1997); Tabrizchi (2001).
Data collection: APEX2 (Bruker, 2001); cell refinement: SAINT (Bruker, 2001); data reduction: SAINT; program(s) used to solve structure: SHELXS97 (Sheldrick, 2008); program(s) used to refine structure: SHELXL97 (Sheldrick, 2008); molecular graphics: ORTEP-3 for Windows (Farrugia, 2012); software used to prepare material for publication: SHELXL97.
Supplementary data and figures for this paper are available from the IUCr electronic archives (Reference: LX2289 ).
We acknowledge NSF funding (CHEM-0131112) for the X-ray diffractometer. We also express gratitude to Oakwood Products, Inc. for the gift of [1-(sulfanylmethyl)cyclopropyl]acetic acid, and to Euticals for the gift of T3P in 2-methyltetrahydrofuran.
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