(a) Macroseeding procedure. The orange and green boxes contain pictures of the crystals after adding 50 and 200 µl of solution A containing protein, respectively. The roman numerals below the pictures correspond to those in (b). (b) Plot of crystal length versus elapsed time. The day on which 50 µl of solution A containing protein (28 mg ml−1) was added is shown as day 0. 200 µl of the same protein solution was added at the point indicated by the green arrow (after 7 d).